Gene Symbol | MUS81 |
Entrez Gene ID | 2539004 |
Full Name | Holliday junction resolvase subunit Mus81 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe 972h- |
ORF » Species Summary » Schizosaccharomyces pombe 972h- » MUS81 cDNA ORF clone
Gene Symbol | MUS81 |
Entrez Gene ID | 2539004 |
Full Name | Holliday junction resolvase subunit Mus81 |
Gene Type | protein-coding |
Organism | Schizosaccharomyces pombe 972h- |
mRNA | Protein | Name |
---|---|---|
NM_001355879.1 | NP_001343019.1 | Holliday junction resolvase subunit Mus81 |
XM_001713109.1 | XP_001713161.1 | Holliday junction resolvase subunit Mus81 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008836 | XP_319580.4 |
Pan troglodytes (chimpanzee) | MUS81 | XP_522066.4 |
MUS81 | XP_001112824.1 | |
Rattus norvegicus (Norway rat) | Mus81 | NP_001020816.1 |
Eremothecium gossypii | AGOS_AFR141C | NP_985688.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04585 | XP_003713609.1 |
Xenopus tropicalis (tropical clawed frog) | mus81 | NP_001011004.1 |
Canis lupus familiaris (dog) | MUS81 | XP_533230.2 |
Mus musculus (house mouse) | Mus81 | NP_082153.3 |
Danio rerio (zebrafish) | mus81 | NP_998683.1 |
Schizosaccharomyces pombe (fission yeast) | mus81 | XP_001713161.1 |
Bos taurus (cattle) | MUS81 | NP_001039756.1 |
Drosophila melanogaster (fruit fly) | mus81 | NP_569873.1 |
Saccharomyces cerevisiae (baker's yeast) | MUS81 | NP_010674.3 |
Kluyveromyces lactis | KLLA0E03015g | XP_454081.1 |
Neurospora crassa | NCU07457 | XP_963908.1 |
Homo sapiens (human) | MUS81 | NP_079404.3 |
The genome sequence of Schizosaccharomyces pombe.
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, Chillingworth T, Churcher C, Collins M, Connor R, Cronin A, Davis P, Feltwell T, Fraser A, Gentles S, Goble A, Hamlin N, Harris D, Hidalgo J, Hodgson G, Holroyd S, Hornsby T, Howarth S, Huckle EJ, Hunt S, Jagels K, James K, Jones L, Jones M, Leather S, McDonald S, McLean J, Mooney P, Moule S, Mungall K, Murphy L, Niblett D, Odell C, Oliver K, O'Neil S, Pearson D, Quail MA, Rabbinowitsch E, Rutherford K, Rutter S, Saunders D, Seeger K, Sharp S, Skelton J, Simmonds M, Squares R, Squares S, Stevens K, Taylor K, Taylor RG, Tivey A, Walsh S, Warren T, Whitehead S, Woodward J, Volckaert G, Aert R, Robben J, Grymonprez B, Weltjens I, Vanstreels E, Rieger M, Sch?fer M, M?ller-Auer S, Gabel C, Fuchs M, D?sterh?ft A, Fritzc C, Holzer E, Moestl D, Hilbert H, Borzym K, Langer I, Beck A, Lehrach H, Reinhardt R, Pohl TM, Eger P, Zimmermann W, Wedler H, Wambutt R, Purnelle B, Goffeau A, Cadieu E, Dr?ano S, Gloux S, Lelaure V, Mottier S, Galibert F, Aves SJ, Xiang Z, Hunt C, Moore K, Hurst SM, Lucas M, Rochet M, Gaillardin C, Tallada VA, Garzon A, Thode G, Daga RR, Cruzado L, Jimenez J, S?nchez M, del Rey F, Benito J, Dom?nguez A, Revuelta JL, Moreno S, Armstrong J, Forsburg SL, Cerutti L, Lowe T, McCombie WR, Paulsen I, Potashkin J, Shpakovski GV, Ussery D, Barrell BG, Nurse P, Cerrutti L
Nature415(6874)871-80(2002 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Removing Rhp51, the Rad51 recombinase homologue, suppresses the slowing defect of rqh1Delta mutants, but not that of mus81Delta mutant, defining an epistatic pathway in which mus81 is epistatic to rhp51 and rhp51 is epistatic to rqh1.
Title: Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint.
Findings demonstrate that Mus81/Eme1 is the dedicated endonuclease that resolves sister chromatid recombination intermediates during the repair of broken replication forks.
Title: Mus81 is essential for sister chromatid recombination at broken replication forks.
An interplay between Mus81 activity at stalled forks and the Chk1-dependent DNA damage checkpoint during S-phase when replication forks have collapsed, was identified.
Title: Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpoint.
The purification of active forms of recombinant Schizosaccharomyces pombe Mus81-Eme1 and Saccharomyces cerevisiae Mus81-Mms4, which display robust Holliday junction cleavage in vitro, is reported.
Title: Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?
Upon S-phase arrest by acute hydroxyurea treatment, Mus81 is not required for cell viability but is essential for recovery from replication fork collapse.
Title: Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress.
The following MUS81 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MUS81 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSj00355 | |
Clone ID Related Accession (Same CDS sequence) | XM_001713109.1 | |
Accession Version | XM_001713109.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2013-04-30 | |
Organism | Schizosaccharomyces pombe 972h- | |
Product | Holliday junction resolvase subunit Mus81 | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). Notes: S. pombe (fission yeast) sequence and annotation are available from: (URL, http://www.genedb.org/genedb/pombe/index.jsp) (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CDS are numbered using the following system eg SPAC5H10.01c. SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), .01 (first CDS), c (complementary strand). However, clones may have been reorientated since the original submission, therefore the complementary strand notation may be invalid for strand inference. |
1 | ATGGATTGTG GAAATCCGCT GTTTTTACAA TGGATACAGG AGTGGATGGA AGAGTCGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_001713161.1 |
CDS | 1..1827 |
Translation |
Target ORF information:
Target ORF information:
|
XM_001713109.1 |
1 | ATGGATTGTG GAAATCCGCT GTTTTTACAA TGGATACAGG AGTGGATGGA AGAGTCGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OSc99876 | |
Clone ID Related Accession (Same CDS sequence) | NM_001355879.1 | |
Accession Version | NM_001355879.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1827bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-04-02 | |
Organism | Schizosaccharomyces pombe(fission yeast) | |
Product | Holliday junction resolvase subunit Mus81 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. This record is derived from an annotated genomic sequence (NC_003421). COMPLETENESS: incomplete on both ends. |
1 | ATGGATTGTG GAAATCCGCT GTTTTTACAA TGGATACAGG AGTGGATGGA AGAGTCGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001343019.1 |
CDS | 1..1827 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001355879.1 |
1 | ATGGATTGTG GAAATCCGCT GTTTTTACAA TGGATACAGG AGTGGATGGA AGAGTCGACG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The genome sequence of Schizosaccharomyces pombe. |