Gene Symbol | RAD3 |
Entrez Gene ID | 856918 |
Full Name | TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3 |
Synonyms | REM1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAD3 cDNA ORF clone
Gene Symbol | RAD3 |
Entrez Gene ID | 856918 |
Full Name | TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3 |
Synonyms | REM1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179061.3 | NP_011098.3 | TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3 |
Mus musculus (house mouse) | Ercc2 | NP_031975.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002988 | XP_311900.4 |
Bos taurus (cattle) | ERCC2 | NP_001096787.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03132 | XP_003716866.1 |
Pan troglodytes (chimpanzee) | ERCC2 | NP_001233519.1 |
Danio rerio (zebrafish) | ercc2 | NP_957220.1 |
Drosophila melanogaster (fruit fly) | Xpd | NP_726036.2 |
Schizosaccharomyces pombe (fission yeast) | rad15 | NP_593025.1 |
Oryza sativa (rice) | Os05g0144800 | NP_001054627.1 |
Xenopus tropicalis (tropical clawed frog) | ercc2 | NP_001008131.1 |
Homo sapiens (human) | ERCC2 | NP_000391.1 |
Canis lupus familiaris (dog) | ERCC2 | XP_541562.3 |
Kluyveromyces lactis | KLLA0C17776g | XP_452994.1 |
Neurospora crassa | NCU01625 | XP_956536.2 |
Arabidopsis thaliana (thale cress) | UVH6 | NP_171818.1 |
LOC715485 | XP_002808245.1 | |
Rattus norvegicus (Norway rat) | Ercc2 | NP_001166280.1 |
Caenorhabditis elegans (roundworm) | Y50D7A.2 | NP_497182.2 |
Saccharomyces cerevisiae (baker's yeast) | RAD3 | NP_011098.3 |
Eremothecium gossypii | AGOS_AGR114C | NP_986780.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Both rad3-101 and rad3-102 elevate the frequency of reciprocal crossovers about 100-fold. Mapping of these events shows that three-quarters of these crossovers reflect DSBs formed at the same positions in both sister chromatids
Title: High-Resolution Mapping of Homologous Recombination Events in rad3 Hyper-Recombination Mutants in Yeast.
When the Rad3 ATP-binding groove is mutated, TFIIH gains a higher affinity for DNA.
Title: The rem mutations in the ATP-binding groove of the Rad3/XPD helicase lead to Xeroderma pigmentosum-Cockayne syndrome-like phenotypes.
In mms19 mutant cells, protein levels of the core TFIIH component Rad3 and Ssl2 were significantly reduced
Title: Mms19 protein functions in nucleotide excision repair by sustaining an adequate cellular concentration of the TFIIH component Rad3.
rad3-102, a mutant allele of the gene RAD3, may increase lesions that elicit a response by the recombination machinery or, alternatively, stabilize recombinagenic lesions generated by DNA replication failure
Title: A mutant allele of the transcription factor IIH helicase gene, RAD3, promotes loss of heterozygosity in response to a DNA replication defect in Saccharomyces cerevisiae.
The following RAD3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAD3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05666 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179061.3 | |
Accession Version | NM_001179061.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2337bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). On Jul 30, 2012 this sequence version replaced NM_001179061.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAAGTTTT ATATAGATGA TTTACCAGTG CTTTTTCCAT ACCCCAAGAT ATATCCAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011098.3 |
CDS | 1..2337 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179061.3 |
1 | ATGAAGTTTT ATATAGATGA TTTACCAGTG CTTTTTCCAT ACCCCAAGAT ATATCCAGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |