Gene Symbol | KAP123 |
Entrez Gene ID | 856846 |
Full Name | Kap123p |
Synonyms | YRB4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » KAP123 cDNA ORF clone
Gene Symbol | KAP123 |
Entrez Gene ID | 856846 |
Full Name | Kap123p |
Synonyms | YRB4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179000.1 | NP_011035.1 | Kap123p |
Pan troglodytes (chimpanzee) | IPO4 | XP_001168091.1 |
Bos taurus (cattle) | IPO4 | NP_001077130.1 |
Danio rerio (zebrafish) | ipo4 | XP_684163.4 |
Drosophila melanogaster (fruit fly) | CG32165 | NP_730182.1 |
Saccharomyces cerevisiae (baker's yeast) | KAP123 | NP_011035.1 |
Eremothecium gossypii | AGOS_AGL298C | NP_986369.2 |
Homo sapiens (human) | IPO4 | NP_078934.3 |
Mus musculus (house mouse) | Ipo4 | NP_077229.4 |
Schizosaccharomyces pombe (fission yeast) | kap123 | NP_596729.1 |
IPO4 | XP_002808502.1 | |
Canis lupus familiaris (dog) | IPO4 | XP_537384.3 |
Drosophila melanogaster (fruit fly) | CG32164 | NP_001261957.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006942 | XP_308814.4 |
Kluyveromyces lactis | KLLA0E20769g | XP_454889.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_16711 | XP_003711698.1 |
Arabidopsis thaliana (thale cress) | AT4G27640 | NP_194494.2 |
Xenopus tropicalis (tropical clawed frog) | ipo4 | NP_001008011.2 |
Rattus norvegicus (Norway rat) | Ipo4 | NP_001099508.1 |
Neurospora crassa | NCU05650 | XP_960211.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
combined impairment of lipid and Kap123 binding affects targeting of Pom33 to NPCs. These data highlight the requirement of multiple determinants and mechanisms for proper NPC localization of Pom33.
Title: Nuclear pore targeting of the yeast Pom33 nucleoporin depends on karyopherin and lipid binding.
The karyopherin Kap123 binds to a nuclear localization sequence next to this amphipathic alpha-helix and prevents unspecific tethering of Nbp1 to membranes.
Title: Targeting of Nbp1 to the inner nuclear membrane is essential for spindle pole body duplication.
Slt2, the mitogen-activated protein kinase of the protein kinase C cell integrity pathway, is constitutively activated in the absence of Kap123, which is consistent with the existence of cell integrity defects.
Title: Yeast karyopherins Kap123 and Kap95 are related to the function of the cell integrity pathway.
A role for the karyopherin Kap123p in microtubule stability is reported.
Title: A role for the karyopherin Kap123p in microtubule stability.
The Kap123p specifically binds to histones H2A and H2B.
Title: The histones H2A/H2B and H3/H4 are imported into the yeast nucleus by different mechanisms.
The following KAP123 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KAP123 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05605 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179000.1 | |
Accession Version | NM_001179000.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3342bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Kap123p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATCAAC AATTTCTAAG TCAACTTGAG CAAACTTTGC ACGCTATCAC TTCTGGTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011035.1 |
CDS | 1..3342 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179000.1 |
1 | ATGGATCAAC AATTTCTAAG TCAACTTGAG CAAACTTTGC ACGCTATCAC TTCTGGTGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |