Gene Symbol | AFG3 |
Entrez Gene ID | 856737 |
Full Name | AAA family ATPase AFG3 |
Synonyms | YTA10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » AFG3 cDNA ORF clone
Gene Symbol | AFG3 |
Entrez Gene ID | 856737 |
Full Name | AAA family ATPase AFG3 |
Synonyms | YTA10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178908.1 | NP_010933.1 | AAA family ATPase AFG3 |
Homo sapiens (human) | AFG3L2 | NP_006787.2 |
Pan troglodytes (chimpanzee) | AFG3L2 | XP_512199.2 |
Saccharomyces cerevisiae (baker's yeast) | AFG3 | NP_010933.1 |
Eremothecium gossypii | AGOS_AAR025C | NP_982566.2 |
Arabidopsis thaliana (thale cress) | ftsh10 | NP_172231.2 |
Bos taurus (cattle) | AFG3L2 | NP_001039676.1 |
Mus musculus (house mouse) | Afg3l2 | NP_081406.1 |
Arabidopsis thaliana (thale cress) | ftsh3 | NP_850129.1 |
AFG3L2 | XP_001094146.1 | |
Gallus gallus (chicken) | AFG3L2 | XP_419121.2 |
Drosophila melanogaster (fruit fly) | CG6512 | NP_730248.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006949 | XP_308807.4 |
Caenorhabditis elegans (roundworm) | spg-7 | NP_491165.2 |
Danio rerio (zebrafish) | afg3l2 | NP_001104667.1 |
Oryza sativa (rice) | Os05g0458400 | NP_001055745.1 |
Canis lupus familiaris (dog) | AFG3L2 | XP_547682.2 |
Rattus norvegicus (Norway rat) | Afg3l2 | NP_001128336.1 |
Oryza sativa (rice) | Os01g0842600 | NP_001044774.1 |
Xenopus tropicalis (tropical clawed frog) | afg3l2 | NP_001072759.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
replacement of the Yta10 TM2 domain abolishes membrane dislocation for only a subset of substrates, whereas replacement of the Yta12 TM2 domain impairs membrane dislocation for all tested substrates, suggesting different roles of the TM domains in each m-AAA protease subunit
Title: Molecular insights into the
Observations show a role for the mitochondrial protease Afg3 in modulating cytoplasmic mRNA translation and ER stress resistance, and suggest Afg3 modulates longevity in yeast by a mechanism similar to cytoplasmic ribosomal large subunit proteins.
Title: Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging.
Inactivation of either of the mitochondrial AAA proteases, Yme1 or Yta10/12, allows fermentative growth of hsc82 or hsp82 strains at 37 degrees C.
Title: Hsp90 and mitochondrial proteases Yme1 and Yta10/12 participate in ATP synthase assembly in Saccharomyces cerevisiae.
Results describe the localizations of the m-AAA protease, its subunits Yta10 and Yta12, and its substrate cytochrome c peroxidase (Ccp1) within yeast mitochondria.
Title: The m-AAA protease processes cytochrome c peroxidase preferentially at the inner boundary membrane of mitochondria.
transmembrane segments of m-AAA protease subunits have a direct role in the dislocation of membrane-embedded substrates
Title: Membrane protein turnover by the m-AAA protease in mitochondria depends on the transmembrane domains of its subunits.
The following AFG3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AFG3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05505 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178908.1 | |
Accession Version | NM_001178908.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2286bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | AAA family ATPase AFG3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGATGATGT GGCAACGATA TGCAAGGGGT GCGCCACGCT CATTGACATC ACTCTCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010933.1 |
CDS | 1..2286 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178908.1 |
1 | ATGATGATGT GGCAACGATA TGCAAGGGGT GCGCCACGCT CATTGACATC ACTCTCATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |