Gene Symbol | SET1 |
Entrez Gene ID | 856519 |
Full Name | histone methyltransferase SET1 |
Synonyms | KMT2,YTX1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SET1 cDNA ORF clone
Gene Symbol | SET1 |
Entrez Gene ID | 856519 |
Full Name | histone methyltransferase SET1 |
Synonyms | KMT2,YTX1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179249.1 | NP_011987.1 | histone methyltransferase SET1 |
Schizosaccharomyces pombe (fission yeast) | set1 | NP_587812.1 |
Saccharomyces cerevisiae (baker's yeast) | SET1 | NP_011987.1 |
Kluyveromyces lactis | KLLA0F24134g | XP_456155.1 |
Eremothecium gossypii | AGOS_ABR136W | NP_983083.2 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Set1 lacking RNA recognition motif 2 (RRM2) showed reduced in vivo cross-linking to RNA and reduced chromatin occupancy. In addition, levels of H3K4 trimethylation were decreased, whereas levels of dimethylation were increased
Title: RNA Binding by Histone Methyltransferases Set1 and Set2.
Set1 and Set5 promote gene silencing at telomeric regions. Double mutants Set1 and Set5 display defects in telomere stability.
Title: The histone methyltransferases Set5 and Set1 have overlapping functions in gene silencing and telomere maintenance.
Transcriptional memory of INO1 requires a remodeled form of the Set1/COMPASS methyltransferase lacking Spp1, which dimethylates histone H3 lysine 4 (H3K4me2).
Title: Set1/COMPASS and Mediator are repurposed to promote epigenetic transcriptional memory.
The study uncovers novel pathways in which the methyltransferase Set5 participates and, more importantly, reveals a partnership between Set1 and Set5 in transcriptional repression near repetitive DNA elements in budding yeast.
Title: Set5 and Set1 cooperate to repress gene expression at telomeres and retrotransposons.
Careful tuning of Set1 levels by regulated degradation is critical for the establishment and maintenance of proper H3K4 methylation patterns.
Title: Feedback control of Set1 protein levels is important for proper H3K4 methylation patterns.
The following SET1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SET1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05317 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179249.1 | |
Accession Version | NM_001179249.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3243bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | histone methyltransferase SET1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001140). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Veresion :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAAATT ACTATAGAAG AGCACACGCG TCTTCTGGTT CATACAGACA ACCCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011987.1 |
CDS | 1..3243 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179249.1 |
1 | ATGTCAAATT ACTATAGAAG AGCACACGCG TCTTCTGGTT CATACAGACA ACCCCAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII. |