Gene Symbol | CUE1 |
Entrez Gene ID | 855306 |
Full Name | Cue1p |
Synonyms | KIS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CUE1 cDNA ORF clone
Gene Symbol | CUE1 |
Entrez Gene ID | 855306 |
Full Name | Cue1p |
Synonyms | KIS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182771.1 | NP_013991.1 | Cue1p |
Saccharomyces cerevisiae (baker's yeast) | CUE1 | NP_013991.1 |
Kluyveromyces lactis | KLLA0E11199g | XP_454454.1 |
Eremothecium gossypii | AGOS_AER279W | NP_985136.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cue1 positions Ubc7 and the distal acceptor ubiquitin for rapid polyubiquitination.
Title: The CUE Domain of Cue1 Aligns Growing Ubiquitin Chains with Ubc7 for Rapid Elongation.
Data indicate that efficient formation of longer ubiquitin chains depends on the Cue1p CUE domain.
Title: Ubiquitin binding by a CUE domain regulates ubiquitin chain formation by ERAD E3 ligases.
Data indicate the crystal structure of the Ubc7p-binding region (U7BR) of Cue1p with Ubc7p.
Title: A structurally unique E2-binding domain activates ubiquitination by the ERAD E2, Ubc7p, through multiple mechanisms.
Data show that a discrete C-terminal Ubc7p binding region of Cue1p is required for ER-associated degradation and for Ubc7p-dependent ubiquitylation by Hrd1p in vitro.
Title: A Ubc7p-binding domain in Cue1p activates ER-associated protein degradation.
reveal a previously unobserved stimulation of Ubc7p E2 activity by Cue1p
Title: Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo.
The following CUE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CUE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04257 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182771.1 | |
Accession Version | NM_001182771.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Cue1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAGGATT CGAGATTGCT TATCACTTTG ATTCTTGTGT TTGGAGTTAT ATTTCTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013991.1 |
CDS | 1..612 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182771.1 |
1 | ATGGAGGATT CGAGATTGCT TATCACTTTG ATTCTTGTGT TTGGAGTTAT ATTTCTGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |