Gene Symbol | PDR5 |
Entrez Gene ID | 854324 |
Full Name | ATP-binding cassette multidrug transporter PDR5 |
Synonyms | LEM1,STS1,YDR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PDR5 cDNA ORF clone
Gene Symbol | PDR5 |
Entrez Gene ID | 854324 |
Full Name | ATP-binding cassette multidrug transporter PDR5 |
Synonyms | LEM1,STS1,YDR1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183572.3 | NP_014796.3 | ATP-binding cassette multidrug transporter PDR5 |
Saccharomyces cerevisiae (baker's yeast) | PDR5 | NP_014796.3 |
Kluyveromyces lactis | KLLA0F21692g | XP_456048.1 |
Arabidopsis thaliana (thale cress) | PDR4 | NP_180259.1 |
Saccharomyces cerevisiae (baker's yeast) | PDR15 | NP_010694.1 |
Saccharomyces cerevisiae (baker's yeast) | PDR10 | NP_014973.1 |
Schizosaccharomyces pombe (fission yeast) | bfr1 | NP_587932.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_13624 | XP_003717522.1 |
Neurospora crassa | NCU05591 | XP_960553.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
structural and functional implications for Pdr5
Title: Transmitting the energy: interdomain cross-talk in Pdr5.
Sequence comparison between the target proteins, i.e., the plant EPSPS and the yeast orthologous protein Aro1, predicted that yeast would be resistant to glyphosate. However, the growth variation seen in the subset of yeast tested was not due to polymorphisms within Aro1, instead, it was caused by genetic variation in an ABC multiple drug transporter, Pdr5, and an amino acid permease, Dip5
Title: Genetic variation in Dip5, an amino acid permease, and Pdr5, a multiple drug transporter, regulates glyphosate resistance in S. cerevisiae.
These results present new evidence, suggesting that transmembrane helix 2 plays an important role for the efflux function of Pdr5p.
Title: Mutations of charged amino acids at the cytoplasmic end of transmembrane helix 2 affect transport activity of the budding yeast multidrug resistance protein Pdr5p.
Pdr5 analyses are applicable to mammalian asymmetric ABC multidrug transporters, including transporter promiscuity, function of non-catalytic ATP-binding site, description of a transmission interface, and discovery that Pdr5 is a molecular diode. Review.
Title: The multidrug transporter Pdr5 on the 25th anniversary of its discovery: an important model for the study of asymmetric ABC transporters.
High-Copy Overexpression Screening Reveals PDR5 as the Main Doxorubicin Resistance Gene in Yeast.
Title: High-Copy Overexpression Screening Reveals PDR5 as the Main Doxorubicin Resistance Gene in Yeast.
The following PDR5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PDR5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03454 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183572.3 | |
Accession Version | NM_001183572.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4536bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ATP-binding cassette multidrug transporter PDR5 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). On Jul 30, 2012 this sequence version replaced NM_001183572.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCCGAGG CCAAGCTTAA CAATAACGTC AACGACGTTA CTAGCTACTC CTCCGCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014796.3 |
CDS | 1..4536 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183572.3 |
1 | ATGCCCGAGG CCAAGCTTAA CAATAACGTC AACGACGTTA CTAGCTACTC CTCCGCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |