Gene Symbol | MDM12 |
Entrez Gene ID | 854153 |
Full Name | ERMES complex subunit MDM12 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MDM12 cDNA ORF clone
Gene Symbol | MDM12 |
Entrez Gene ID | 854153 |
Full Name | ERMES complex subunit MDM12 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183263.1 | NP_014634.1 | ERMES complex subunit MDM12 |
Schizosaccharomyces pombe (fission yeast) | mdm12 | NP_595667.1 |
Eremothecium gossypii | AGOS_ACL013C | NP_983391.2 |
Neurospora crassa | NCU02067 | XP_964594.1 |
Saccharomyces cerevisiae (baker's yeast) | MDM12 | NP_014634.1 |
Kluyveromyces lactis | KLLA0C06028g | XP_452466.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08869 | XP_003713895.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mdm34 and Mdm12, 2 components of the endoplasmic reticulum-mitochondrial encounter structure, are ubiquitinated by the E3 ligase Rsp5
Title: Ubiquitination of ERMES components by the E3 ligase Rsp5 is involved in mitophagy.
These studies provide a novel understanding of the overall organization of SMP domains in the endoplasmic reticulum-mitochondria encounter structure (ERMES) complex, indicating that Mdm12 interacts with Mdm34 through head-to-head contact, and with Mmm1 through tail-to-tail contact of SMP domains.
Title: Crystal structure of Mdm12 reveals the architecture and dynamic organization of the ERMES complex.
Assembly of mitochondrial beta-barrel proteins represents a major function of the morphology proteins Mdm12/Mmm1.
Title: The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria.
The following MDM12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MDM12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03307 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183263.1 | |
Accession Version | NM_001183263.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ERMES complex subunit MDM12 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTTTTG ATATTAATTG GAGTACATTG GAATCTGACA ATAGACTGAA TGATCTTATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014634.1 |
CDS | 1..816 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183263.1 |
1 | ATGTCTTTTG ATATTAATTG GAGTACATTG GAATCTGACA ATAGACTGAA TGATCTTATA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |