NPA3 cDNA ORF clone, Saccharomyces cerevisiae S288C

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)

Npa3/Gpn1 carboxy-terminal tail is dispensable for cell viability and RNA polymerase II nuclear targeting but critical for microtubule stability and function.
Title: Npa3/ScGpn1 carboxy-terminal tail is dispensable for cell viability and RNA polymerase II nuclear targeting but critical for microtubule stability and function.

Npa3 has chaperone activity and interacts with hydrophobic peptide regions of RNA Polymerase II subunits that form interfaces in the assembled RNA Polymerase II complex.
Title: Structure of GPN-Loop GTPase Npa3 and Implications for RNA Polymerase II Assembly.

These results suggest that yGPN1 and yGPN2, yGPN3 proteins act at the molecular level in sister chromatid cohesion mechanism as a GPN|GPN complex.
Title: Eukaryotic GPN-loop GTPases paralogs use a dimeric assembly reminiscent of archeal GPN.

Npa3 defines an unconventional pathway for nuclear import of RNAPII, which involves GTP-dependent binding of Npa3 to the polymerase.
Title: GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein.