Gene Symbol | THG1 |
Entrez Gene ID | 852908 |
Full Name | tRNA guanylyltransferase |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » THG1 cDNA ORF clone
Gene Symbol | THG1 |
Entrez Gene ID | 852908 |
Full Name | tRNA guanylyltransferase |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181153.3 | NP_011538.3 | tRNA guanylyltransferase |
Pan troglodytes (chimpanzee) | THG1L | XP_518066.2 |
Bos taurus (cattle) | THG1L | NP_001073702.1 |
Mus musculus (house mouse) | Thg1l | NP_001074438.1 |
Danio rerio (zebrafish) | thg1l | NP_001007456.1 |
Saccharomyces cerevisiae (baker's yeast) | THG1 | NP_011538.3 |
Neurospora crassa | NCU02105 | XP_964099.2 |
Arabidopsis thaliana (thale cress) | AT2G31580 | NP_565727.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100487878 | XP_004912832.1 |
THG1L | XP_001113603.1 | |
Canis lupus familiaris (dog) | THG1L | XP_536453.2 |
Eremothecium gossypii | AGOS_ABR031C | NP_982977.1 |
Xenopus tropicalis (tropical clawed frog) | LOC101733043 | XP_004920397.1 |
Gallus gallus (chicken) | THG1L | NP_001025787.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011752 | XP_320758.4 |
Homo sapiens (human) | THG1L | NP_060342.2 |
Drosophila melanogaster (fruit fly) | l(2)35Bc | NP_001188815.1 |
Kluyveromyces lactis | KLLA0B06237g | XP_451814.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_14742 | XP_003713640.1 |
Arabidopsis thaliana (thale cress) | AT2G32320 | NP_001154545.1 |
Oryza sativa (rice) | Os05g0535500 | NP_001056156.1 |
Rattus norvegicus (Norway rat) | Thg1l | NP_001013988.1 |
Schizosaccharomyces pombe (fission yeast) | SPCC63.07 | NP_587981.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study determined the crystal structure of GTP-bound Thg1 from Saccharomyces cerevisiae at the maximum resolution of 3.0 A.
Title: Crystal structure of tRNA
pyrophosphate removal versus nucleotide addition activities of yeast Thg1 with a set of tRNA(His) substrates
Title: Saccharomyces cerevisiae Thg1 uses 5'-pyrophosphate removal to control addition of nucleotides to tRNA(His.).
Study provides the first kinetic insight into the individual steps of the non-Watson-Crick addition of G- to tRNAHis, the known physiological function of Thg1 in yeast.
Title: Kinetic analysis of 3'-5' nucleotide addition catalyzed by eukaryotic tRNA(His) guanylyltransferase.
Thg1 substrate recognition is at least in part mediated by preventing recognition of incorrect substrates for nucleotide addition
Title: Identification of critical residues for G-1 addition and substrate recognition by tRNA(His) guanylyltransferase.
These results suggest that 3'-5' polymerization represents either an uncharacterized role for Thg1 in RNA or DNA repair or metabolism, or it may be a remnant of an earlier catalytic strategy used in nature.
Title: tRNAHis guanylyltransferase catalyzes a 3'-5' polymerization reaction that is distinct from G-1 addition.
The following THG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the THG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02254 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181153.3 | |
Accession Version | NM_001181153.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | tRNA guanylyltransferase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001181153.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCAAACT CTAAATTTGG ATACGTAAGG CAATTTGAAA CACACGATGT TATTTTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011538.3 |
CDS | 1..714 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181153.3 |
1 | ATGGCAAACT CTAAATTTGG ATACGTAAGG CAATTTGAAA CACACGATGT TATTTTGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |