Gene Symbol | OLE1 |
Entrez Gene ID | 852825 |
Full Name | stearoyl-CoA 9-desaturase |
Synonyms | MDM2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » OLE1 cDNA ORF clone
Gene Symbol | OLE1 |
Entrez Gene ID | 852825 |
Full Name | stearoyl-CoA 9-desaturase |
Synonyms | MDM2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180920.3 | NP_011460.3 | stearoyl-CoA 9-desaturase |
Saccharomyces cerevisiae (baker's yeast) | OLE1 | NP_011460.3 |
Kluyveromyces lactis | KLLA0C05566g | XP_452447.1 |
Schizosaccharomyces pombe (fission yeast) | SPCC1281.06c | NP_588170.1 |
Neurospora crassa | NCU05259 | XP_961824.1 |
Rattus norvegicus (Norway rat) | Scd | NP_114029.1 |
Eremothecium gossypii | AGOS_AAR153C | NP_982696.1 |
Drosophila melanogaster (fruit fly) | CG8630 | NP_731781.1 |
Caenorhabditis elegans (roundworm) | fat-6 | NP_001255595.1 |
Caenorhabditis elegans (roundworm) | fat-5 | NP_507482.1 |
Mus musculus (house mouse) | Scd2 | NP_033154.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003418 | XP_311704.5 |
Caenorhabditis elegans (roundworm) | fat-7 | NP_504814.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01790 | XP_003714796.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Studied osmotic stress tolerance in Saccharomyces cerevisiae; found OLE1 overexpression improves stress tolerance and activates Hog1 pathway.
Title: Overexpression of OLE1 enhances stress tolerance and constitutively activates the MAPK HOG pathway in Saccharomyces cerevisiae.
role of OLE pathway in the maintenance of membrane fluidity
Title: Control of membrane fluidity: the OLE pathway in focus.
data suggest that the regulation of OLE1 in the synthesis of unsaturated fatty acids may serve as a positive feedback mechanism to help yeast cells counter the lipid peroxidation and cytoplasmic membrane damage caused by cadmium. The discovery of OLE1 involvement in membrane stability may indicate a novel defense strategy against cadmium stress [
Title: Overexpression of OLE1 Enhances Cytoplasmic Membrane Stability and Confers Resistance to Cadmium in Saccharomyces cerevisiae.
Ole1 partially relieves the growth defects of endoplasmic reticulum-mitochondria encounter structure -lacking cells.
Title: Identification of multi-copy suppressors for endoplasmic reticulum-mitochondria tethering proteins in Saccharomyces cerevisiae.
novel mechanism for the regulation of fatty acid desaturation that is based on competition between Ole1p and the glycerol-3-phosphate acyltransferase Sct1p/Gat2p for the common substrate C16:0-CoA
Title: The yeast acyltransferase Sct1p regulates fatty acid desaturation by competing with the desaturase Ole1p.
The following OLE1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OLE1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02186 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180920.3 | |
Accession Version | NM_001180920.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1533bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | stearoyl-CoA 9-desaturase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001180920.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCAACTT CTGGAACTAC TATTGAATTG ATTGACGACC AATTTCCAAA GGATGACTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011460.3 |
CDS | 1..1533 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180920.3 |
1 | ATGCCAACTT CTGGAACTAC TATTGAATTG ATTGACGACC AATTTCCAAA GGATGACTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |