Gene Symbol | MTO1 |
Entrez Gene ID | 852616 |
Full Name | tRNA modification protein MTO1 |
Synonyms | IPS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MTO1 cDNA ORF clone
Gene Symbol | MTO1 |
Entrez Gene ID | 852616 |
Full Name | tRNA modification protein MTO1 |
Synonyms | IPS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181102.1 | NP_011278.2 | tRNA modification protein MTO1 |
Canis lupus familiaris (dog) | MTO1 | XP_532202.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007661 | XP_308209.4 |
Magnaporthe oryzae (rice blast fungus) | MGG_14754 | XP_003713873.1 |
Danio rerio (zebrafish) | mto1 | NP_001076478.1 |
Caenorhabditis elegans (roundworm) | F52H3.2 | NP_496169.1 |
Eremothecium gossypii | AGOS_AFR255W | NP_985802.2 |
Oryza sativa (rice) | Os01g0960300 | NP_001045465.1 |
Homo sapiens (human) | MTO1 | NP_001116698.1 |
Pan troglodytes (chimpanzee) | MTO1 | XP_003311451.1 |
Saccharomyces cerevisiae (baker's yeast) | MTO1 | NP_011278.2 |
Kluyveromyces lactis | KLLA0A00935g | XP_451040.1 |
Schizosaccharomyces pombe (fission yeast) | SPBC30B4.06c | NP_595531.1 |
Neurospora crassa | NCU11170 | XP_956189.2 |
Bos taurus (cattle) | MTO1 | NP_001069537.1 |
Mus musculus (house mouse) | Mto1 | NP_080934.2 |
Rattus norvegicus (Norway rat) | Mto1 | NP_001100311.1 |
Gallus gallus (chicken) | MTO1 | NP_001073232.1 |
Drosophila melanogaster (fruit fly) | CG4610 | NP_611677.1 |
Arabidopsis thaliana (thale cress) | AT2G13440 | NP_178974.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The deletion of the nuclear gene MTO1 regulates neomycin sensitivity in yeast carrying the mitochondrial 15S rRNA C1477G mutation.
Title: MTO1 worked as a modifier in the aminoglycosides sensitivity of yeast carrying a mitochondrial 15S rRNA C1477G mutation.
The respiratory yeast phenotype for MTO1 was dramatically worsened in stress conditions and in the presence of a paromomycin-resistant (P(R)) mitochondrial rRNA mutation
Title: Mutations of the mitochondrial-tRNA modifier MTO1 cause hypertrophic cardiomyopathy and lactic acidosis.
These data strongly indicate that unmodified tRNA caused by the deletion of MTO1 gene caused the instability of mitochondrial tRNAs and mRNAs and an impairment of aminoacylation of mitochondrial tRNAs.
Title: Mutation in MTO1 involved in tRNA modification impairs mitochondrial RNA metabolism in the yeast Saccharomyces cerevisiae.
The following MTO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MTO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02005 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181102.1 | |
Accession Version | NM_001181102.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2010bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | tRNA modification protein MTO1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCTGCGTG TAACAACCTT GGCGTCTTCG TGTACTTCAT TTCCCTTACA GGTCCTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011278.2 |
CDS | 1..2010 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181102.1 |
1 | ATGCTGCGTG TAACAACCTT GGCGTCTTCG TGTACTTCAT TTCCCTTACA GGTCCTCAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |