Gene Symbol | SCM3 |
Entrez Gene ID | 851416 |
Full Name | Scm3p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SCM3 cDNA ORF clone
Gene Symbol | SCM3 |
Entrez Gene ID | 851416 |
Full Name | Scm3p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180199.1 | NP_010142.2 | Scm3p |
Kluyveromyces lactis | KLLA0F05115g | XP_455312.1 |
Saccharomyces cerevisiae (baker's yeast) | SCM3 | NP_010142.2 |
Eremothecium gossypii | AGOS_ADR088C | NP_984184.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cse4 and H3 are structurally compatible to be incorporated in the same nucleosome to form heterotypic particles during Scm3-mediated nucleosome assembly.
Title: Scm3 deposits a (Cse4-H4)2 tetramer onto DNA through a Cse4-H4 dimer intermediate.
Scm3 becomes 2.5-fold enriched at kinetochores in anaphase after incorporation of Ces4 and then dissociated from kinetochores with mitotic exit.
Title: The CENP-A chaperone Scm3 becomes enriched at kinetochores in anaphase independently of CENP-A incorporation.
stringent regulation of HJURP and SCM3 expression are critical for genome stability.
Title: Misregulation of Scm3p/HJURP causes chromosome instability in Saccharomyces cerevisiae and human cells.
Study propose that Scm3 plays an active role in centromeric nucleosome assembly.
Title: Scm3 is a centromeric nucleosome assembly factor.
Scm3 functions as a Cse4-specific nucleosome assembly factor, and the resulting octameric nucleosomes do not contain Scm3 as a stably bound component.
Title: Structure and Scm3-mediated assembly of budding yeast centromeric nucleosomes.
The following SCM3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SCM3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00966 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180199.1 | |
Accession Version | NM_001180199.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 672bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Scm3p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAAAACCA ATAAGAAAAT TTCTAAAAGA AGAAGCCTGA AAAATCTCCA TGGTGCCTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010142.2 |
CDS | 1..672 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180199.1 |
1 | ATGAAAACCA ATAAGAAAAT TTCTAAAAGA AGAAGCCTGA AAAATCTCCA TGGTGCCTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |