Gene Symbol | RFA1 |
Entrez Gene ID | 851266 |
Full Name | replication factor A subunit protein RFA1 |
Synonyms | BUF2,FUN3,RPA1,RPA70 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RFA1 cDNA ORF clone
Gene Symbol | RFA1 |
Entrez Gene ID | 851266 |
Full Name | replication factor A subunit protein RFA1 |
Synonyms | BUF2,FUN3,RPA1,RPA70 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178211.1 | NP_009404.1 | replication factor A subunit protein RFA1 |
Drosophila melanogaster (fruit fly) | RpA-70 | NP_524274.1 |
Saccharomyces cerevisiae (baker's yeast) | RFA1 | NP_009404.1 |
Kluyveromyces lactis | KLLA0A08844g | XP_451388.1 |
Eremothecium gossypii | AGOS_AFL008W | NP_985540.1 |
Arabidopsis thaliana (thale cress) | RPA70C | NP_199353.1 |
Mus musculus (house mouse) | Rpa1 | NP_001157695.1 |
Rattus norvegicus (Norway rat) | Rpa1 | NP_001041308.1 |
Danio rerio (zebrafish) | rpa1 | NP_956105.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001421 | XP_321709.4 |
Schizosaccharomyces pombe (fission yeast) | ssb1 | NP_595092.1 |
Canis lupus familiaris (dog) | RPA1 | XP_003639310.1 |
Oryza sativa (rice) | Os05g0111000 | NP_001054445.1 |
Xenopus tropicalis (tropical clawed frog) | rpa1 | NP_001015732.1 |
Homo sapiens (human) | RPA1 | NP_002936.1 |
Pan troglodytes (chimpanzee) | RPA1 | XP_511254.3 |
Bos taurus (cattle) | RPA1 | NP_001068644.1 |
Gallus gallus (chicken) | RPA1 | NP_001006221.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00685 | XP_003718324.1 |
Neurospora crassa | NCU03606 | XP_961333.1 |
Arabidopsis thaliana (thale cress) | AT4G19130 | NP_567576.2 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
RPA-dependent recruitment of Mec1-Ddc2 is crucial for maintaining its homodimeric state at ssDNA and that Ddc2's recruitment domain and CCD are important for Mec1-dependent survival of UV-light-induced DNA damage.
Title: Structural Basis of Mec1-Ddc2-RPA Assembly and Activation on Single-Stranded DNA at Sites of Damage.
Overexpression of Rad51 was also found to suppress the rfa1 BIR defects. We suggest that Rad51 binding to the ssDNA formed by excessive end resection and during D-loop migration can partially compensate for dysfunctional RPA.
Title: RPA Stabilization of Single-Stranded DNA Is Critical for Break-Induced Replication.
Force regulated dynamics of RPA1 on a DNA fork during DNA replication has been reported.
Title: Force regulated dynamics of RPA on a DNA fork.
secondary structures within single-stranded DNA are potent instigators of genome instability, and RPA and Mre11-Sae2 play important roles in preventing their formation and propagation, respectively.
Title: Mre11-Sae2 and RPA Collaborate to Prevent Palindromic Gene Amplification.
DNA break induction, the budding yeast SUMO ligase Siz2 collaborates with the ssDNA-binding complex RPA (replication protein A) to induce the sumoylation of recombination factors and confer damage resistance
Title: DNA break-induced sumoylation is enabled by collaboration between a SUMO ligase and the ssDNA-binding complex RPA.
The following RFA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RFA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00845 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178211.1 | |
Accession Version | NM_001178211.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1866bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | replication factor A subunit protein RFA1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGCAGTG TTCAACTTTC GAGGGGCGAT TTTCATAGCA TCTTCACCAA TAAGCAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009404.1 |
CDS | 1..1866 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178211.1 |
1 | ATGAGCAGTG TTCAACTTTC GAGGGGCGAT TTTCATAGCA TCTTCACCAA TAAGCAAAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |