Gene Symbol | DRS2 |
Entrez Gene ID | 851207 |
Full Name | aminophospholipid-translocating P4-type ATPase DRS2 |
Synonyms | FUN38,SWA3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » DRS2 cDNA ORF clone
Gene Symbol | DRS2 |
Entrez Gene ID | 851207 |
Full Name | aminophospholipid-translocating P4-type ATPase DRS2 |
Synonyms | FUN38,SWA3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178171.2 | NP_009376.2 | aminophospholipid-translocating P4-type ATPase DRS2 |
Canis lupus familiaris (dog) | ATP8A2 | XP_003433345.1 |
Bos taurus (cattle) | ATP8A2 | NP_001157274.3 |
Gallus gallus (chicken) | ATP8A2 | XP_417130.4 |
Saccharomyces cerevisiae (baker's yeast) | DRS2 | NP_009376.2 |
Neurospora crassa | NCU00352 | XP_957823.1 |
Homo sapiens (human) | ATP8A2 | NP_057613.4 |
Mus musculus (house mouse) | Atp8a2 | NP_056618.1 |
Danio rerio (zebrafish) | atp8a2 | XP_005162794.1 |
Kluyveromyces lactis | KLLA0A04015g | XP_451177.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_12922 | XP_003712724.1 |
Oryza sativa (rice) | Os10g0412000 | NP_001064586.1 |
Pan troglodytes (chimpanzee) | ATP8A2 | XP_522636.3 |
Schizosaccharomyces pombe (fission yeast) | SPBC887.12 | NP_596486.1 |
Arabidopsis thaliana (thale cress) | ALA3 | NP_176191.1 |
ATP8A2 | XP_001092901.2 | |
Rattus norvegicus (Norway rat) | LOC691889 | XP_003751540.1 |
Eremothecium gossypii | AGOS_ADR350W | NP_984446.2 |
Xenopus tropicalis (tropical clawed frog) | atp8a2 | XP_004912100.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae.
Bussey H, Kaback DB, Zhong W, Vo DT, Clark MW, Fortin N, Hall J, Ouellette BF, Keng T, Barton AB
Proceedings of the National Academy of Sciences of the United States of America92(9)3809-13(1995 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
activation of the Drs2p-Cdc50p flippase follows a multistep mechanism, with preliminary release of a number of constraints, possibly through the binding of regulatory proteins in the trans-Golgi network, followed by full activation by PI4P
Title: High phosphatidylinositol 4-phosphate (PI4P)-dependent ATPase activity for the Drs2p-Cdc50p flippase after removal of its N- and C-terminal extensions.
we describe the overexpression of a yeast lipid flippase complex, namely the P4-ATPase Drs2p and its associated subunit Cdc50p, in a coordinated manner.
Title: Coordinated Overexpression in Yeast of a P4-ATPase and Its Associated Cdc50 Subunit: The Case of the Drs2p/Cdc50p Lipid Flippase Complex.
Deletion of KES1 suppresses plasma membrane-missorting defects and the accumulation of intracellular ergosterol in drs2 mutants.
Title: Phosphatidylserine translocation at the yeast trans-Golgi network regulates protein sorting into exocytic vesicles.
Imh1p and Drs2p modulate the activity of Gcs1p by timing its interaction with Arl1p, hence providing feedback regulation of Arl1p activity.
Title: Mechanism of action of the flippase Drs2p in modulating GTP hydrolysis of Arl1p.
Auto-inhibition of Drs2p, a yeast phospholipid flippase, by its carboxyl-terminal tail.
Title: Auto-inhibition of Drs2p, a yeast phospholipid flippase, by its carboxyl-terminal tail.
The following DRS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DRS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00793 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178171.2 | |
Accession Version | NM_001178171.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4068bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | aminophospholipid-translocating P4-type ATPase DRS2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001133). On Apr 26, 2011 this sequence version replaced NM_001178171.1. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAATGACG ACAGAGAAAC CCCCCCAAAG AGGAAACCTG GGGAGGACGA CACGCTTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009376.2 |
CDS | 1..4068 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178171.2 |
1 | ATGAATGACG ACAGAGAAAC CCCCCCAAAG AGGAAACCTG GGGAGGACGA CACGCTTTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
The nucleotide sequence of chromosome I from Saccharomyces cerevisiae. |