Gene Symbol | GCD7 |
Entrez Gene ID | 850998 |
Full Name | translation initiation factor eIF2B subunit beta |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » GCD7 cDNA ORF clone
Gene Symbol | GCD7 |
Entrez Gene ID | 850998 |
Full Name | translation initiation factor eIF2B subunit beta |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182179.1 | NP_013394.1 | translation initiation factor eIF2B subunit beta |
Danio rerio (zebrafish) | eif2b2 | NP_998068.1 |
Drosophila melanogaster (fruit fly) | eIF2B-beta | NP_570020.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007097 | XP_308661.3 |
Arabidopsis thaliana (thale cress) | AT3G07300 | NP_001030655.1 |
Pan troglodytes (chimpanzee) | EIF2B2 | XP_001159118.1 |
EIF2B2 | XP_001096586.1 | |
Canis lupus familiaris (dog) | EIF2B2 | XP_547911.3 |
Bos taurus (cattle) | EIF2B2 | NP_001015593.1 |
Kluyveromyces lactis | KLLA0C05082g | XP_452427.1 |
Homo sapiens (human) | EIF2B2 | NP_055054.1 |
Rattus norvegicus (Norway rat) | Eif2b2 | NP_114447.2 |
Saccharomyces cerevisiae (baker's yeast) | GCD7 | NP_013394.1 |
Mus musculus (house mouse) | Eif2b2 | NP_663420.1 |
Gallus gallus (chicken) | EIF2B2 | NP_001006481.1 |
Kluyveromyces lactis | KLLA0A04433g | XP_451194.1 |
Eremothecium gossypii | AGOS_AGR292C | NP_986958.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC343.14c | NP_593435.1 |
Oryza sativa (rice) | Os10g0392700 | NP_001064516.2 |
Xenopus tropicalis (tropical clawed frog) | eif2b2 | NP_001164986.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
findings provide compelling evidence that beta/Gcd7 is crucial for binding of substrate by eIF2B in vivo, beyond its dispensable regulatory role in the inhibition of eIF2B by eIF
Title: The beta/Gcd7 subunit of eukaryotic translation initiation factor 2B (eIF2B), a guanine nucleotide exchange factor, is crucial for binding eIF2 in vivo.
These data show that multiple contacts between eIF2gamma and eIF2Bepsilon mediate nucleotide exchange.
Title: Critical contacts between the eukaryotic initiation factor 2B (eIF2B) catalytic domain and both eIF2beta and -2gamma mediate guanine nucleotide exchange.
The eIF2/eIF5 complex represents a cytoplasmic reservoir for eIF2 that antagonizes eIF2B-promoted guanine nucleotide exchange, enabling coordinated regulation of translation initiation.
Title: An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.
The following GCD7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GCD7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00620 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182179.1 | |
Accession Version | NM_001182179.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1146bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | translation initiation factor eIF2B subunit beta | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001144). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCCTCTC AAGCATTCAC TTCAGTACAT CCGAATGCGG CAACATCTGA TGTGAATGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013394.1 |
CDS | 1..1146 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182179.1 |
1 | ATGTCCTCTC AAGCATTCAC TTCAGTACAT CCGAATGCGG CAACATCTGA TGTGAATGTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. |
Life with 6000 genes. |