Gene Symbol | UPS1 |
Entrez Gene ID | 850890 |
Full Name | Ups1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » UPS1 cDNA ORF clone
Gene Symbol | UPS1 |
Entrez Gene ID | 850890 |
Full Name | Ups1p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182080.1 | NP_013294.1 | Ups1p |
Saccharomyces cerevisiae (baker's yeast) | UPS1 | NP_013294.1 |
Homo sapiens (human) | PRELID1 | NP_037369.1 |
Rattus norvegicus (Norway rat) | Prelid1 | NP_001009636.1 |
Danio rerio (zebrafish) | prelid1a | NP_956660.1 |
Kluyveromyces lactis | KLLA0E19581g | XP_454837.1 |
PRELID1 | XP_001088735.1 | |
Drosophila melanogaster (fruit fly) | prel | NP_610487.3 |
Pan troglodytes (chimpanzee) | PRELID1 | NP_001238832.1 |
Gallus gallus (chicken) | PRELID1 | NP_990303.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010959 | XP_563974.2 |
Eremothecium gossypii | AGOS_AAR075C | NP_982616.1 |
Schizosaccharomyces pombe (fission yeast) | SPAP8A3.10 | NP_594949.1 |
Xenopus tropicalis (tropical clawed frog) | prelid1 | NP_001016173.1 |
Canis lupus familiaris (dog) | PRELID1 | XP_852403.1 |
Bos taurus (cattle) | PRELID1 | NP_001033227.1 |
Mus musculus (house mouse) | Prelid1 | NP_079872.4 |
Caenorhabditis elegans (roundworm) | CELE_B0334.4 | NP_496457.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Johnston M, Hillier L, Riles L, Albermann K, Andr? B, Ansorge W, Benes V, Br?ckner M, Delius H, Dubois E, D?sterh?ft A, Entian KD, Floeth M, Goffeau A, Hebling U, Heumann K, Heuss-Neitzel D, Hilbert H, Hilger F, Kleine K, K?tter P, Louis EJ, Messenguy F, Mewes HW, Hoheisel JD
Nature387(6632 Suppl)87-90(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The Ups1-Mdm35 complex constitutes a single domain that has a deep pocket and flexible Omega-loop lid. A basic residue at the pocket bottom and the Omega-loop lid are important for phosphatidic acid extraction from the membrane following Ups1 binding.
Title: Structural and mechanistic insights into phospholipid transfer by Ups1-Mdm35 in mitochondria.
crystal structure of Ups1-Mdm35 bound with a phosphatidic acid (PA) molecule at 2.0 A resolution; study reveals molecular basis of Ups1-Mdm35-mediated PA binding and transfer and sheds new light on mechanism of intramitochondrial lipid transport by MSF1/PRELI family proteins
Title: Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex.
PS is transferred from the mitochondrial outer membrane to the inner membrane independently of Psd1p, Ups1p, and Ups2p and decarboxylated to PE by Psd1p in the inner membrane
Title: Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P.
study identified Ups1 as a lipid transfer protein that can shuttle phosphatidic acid between mitochondrial membranes; lipid transfer required the dynamic assembly of Ups1 with Mdm35 and allowed conversion of phosphatidic acid to cardiolipin in the inner membrane
Title: Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein.
Data suggest that Ups1p and Up2p proteins may function in phospholipid trafficking between the outer and inner mitochondrial membranes.
Title: Role for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking.
The following UPS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UPS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00531 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182080.1 | |
Accession Version | NM_001182080.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Ups1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001144). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGTCCTTT TACACAAAAG CACACATATA TTTCCTACCG ATTTTGCCTC TGTTTCACGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013294.1 |
CDS | 1..528 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182080.1 |
1 | ATGGTCCTTT TACACAAAAG CACACATATA TTTCCTACCG ATTTTGCCTC TGTTTCACGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII. |
Life with 6000 genes. |