Gene Symbol | SMC1 |
Entrez Gene ID | 850540 |
Full Name | cohesin subunit SMC1 |
Synonyms | CHL10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SMC1 cDNA ORF clone
Gene Symbol | SMC1 |
Entrez Gene ID | 850540 |
Full Name | cohesin subunit SMC1 |
Synonyms | CHL10 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179958.1 | NP_116647.1 | cohesin subunit SMC1 |
Canis lupus familiaris (dog) | SMC1A | XP_538049.3 |
Danio rerio (zebrafish) | smc1a | NP_001155103.1 |
Schizosaccharomyces pombe (fission yeast) | psm1 | NP_596049.2 |
Mus musculus (house mouse) | Smc1a | NP_062684.2 |
Caenorhabditis elegans (roundworm) | him-1 | NP_001040658.2 |
SMC1A | XP_001091228.1 | |
Arabidopsis thaliana (thale cress) | TTN8 | NP_001190092.1 |
Oryza sativa (rice) | Os12g0641500 | NP_001067404.1 |
Danio rerio (zebrafish) | smc1al | NP_997975.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002947 | XP_311953.3 |
Saccharomyces cerevisiae (baker's yeast) | SMC1 | NP_116647.1 |
Kluyveromyces lactis | KLLA0D07502g | XP_453397.1 |
Eremothecium gossypii | AGOS_AGL023W | NP_986643.1 |
Homo sapiens (human) | SMC1A | NP_006297.2 |
Pan troglodytes (chimpanzee) | SMC1A | XP_003954052.1 |
Bos taurus (cattle) | SMC1A | NP_777039.1 |
Rattus norvegicus (Norway rat) | Smc1a | NP_113871.1 |
Gallus gallus (chicken) | SMC1A | NP_989847.1 |
Drosophila melanogaster (fruit fly) | SMC1 | NP_651211.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_16203 | XP_003709622.1 |
Neurospora crassa | NCU01323 | XP_961409.2 |
Xenopus tropicalis (tropical clawed frog) | LOC100493711 | XP_002935560.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae.
Murakami Y, Naitou M, Hagiwara H, Shibata T, Ozawa M, Sasanuma S, Sasanuma M, Tsuchiya Y, Soeda E, Yokoyama K
Nature genetics10(3)261-8(1995 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
A reversible association between Smc1 and Smc3 coiled coils is regulated by lysine acetylation and is required for cohesin association with the DNA.
Title: A Reversible Association between Smc Coiled Coils Is Regulated by Lysine Acetylation and Is Required for Cohesin Association with the DNA.
We identified a large number of mutations in the CC region of both Smc1 and Smc3... we introduced them to the yeast Smc1 and Smc3 CC domains and characterized the effect of these mutant alleles on cohesin's function. We identified a missense mutation in the region of the kink domain of Smc3, which was previously identified in kidney carcinoma
Title: Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.
These results also suggest that Eco1 promotes cohesion by modulating the ATPase cycle of DNA-bound cohesin in a state that is permissive for DNA tethering and refractory to Wpl1 inhibition.
Title: The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering.
Smc5/6 and cohesin complexes are interrelated and cooperating factors that control chromosome dynamics throughout interphase. [review]
Title: Functional interplay between cohesin and Smc5/6 complexes.
by retarding Topo II-driven decatenation, cohesin (Smc1, Smc3, Scc1) mediates sister chromatid cohesion by an indirect mechanism as well as one involving entrapment of sister DNAs inside its tripartite ring
Title: Cohesin's concatenation of sister DNAs maintains their intertwining.
The following SMC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SMC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00228 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179958.1 | |
Accession Version | NM_001179958.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3678bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cohesin subunit SMC1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001138). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGACGTT TAGTTGGCTT AGAACTAAGT AATTTCAAGT CCTATAGAGG CGTTACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_116647.1 |
CDS | 1..3678 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179958.1 |
1 | ATGGGACGTT TAGTTGGCTT AGAACTAAGT AATTTCAAGT CCTATAGAGG CGTTACCAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae. |