OXA1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene
Clones
gRNAs

Summary

Gene Symbol	OXA1
Entrez Gene ID	856898
Full Name	membrane insertase OXA1
Gene Type	protein-coding
Organism	Saccharomyces cerevisiae S288C

mRNA and Protein(s)

mRNA	Protein	Name
NM_001179044.1	NP_011081.1	membrane insertase OXA1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	OXA1L	XP_509840.2
Rattus norvegicus (Norway rat)	Oxa1l	NP_001162055.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP005421	XP_315429.4
	OXA1L	XP_001099660.1
Caenorhabditis elegans (roundworm)	C01A2.3	NP_493356.2
Saccharomyces cerevisiae (baker's yeast)	OXA1	NP_011081.1
Xenopus tropicalis (tropical clawed frog)	oxa1l	NP_001106402.1
Canis lupus familiaris (dog)	OXA1L	XP_005623266.1
Bos taurus (cattle)	OXA1L	NP_001030412.1
Mus musculus (house mouse)	Oxa1l	NP_081212.1
Danio rerio (zebrafish)	oxa1l	NP_001098600.2
Homo sapiens (human)	OXA1L	NP_005006.3
Drosophila melanogaster (fruit fly)	CG6404	NP_729634.1
Kluyveromyces lactis	KLLA0E00925g	XP_453990.1
Eremothecium gossypii	AGOS_AGR143W	NP_986809.1

Gene Ontology
Bibliography

Related articles in PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that Escherichia coli Ffh protein bound to the large subunit of mitochondrial ribosomes, and could relieve, to some degree, the defect of Saccharomyces cerevisiae Oxa1 mutants.
Title: Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle provides insights into the evolution of the cotranslational insertion systems.

observations suggest that the function of Oxa1 is relevant not only for the biogenesis of conserved mitochondrial components such as respiratory chain complexes or ABC transporters but also for mitochondria-specific membrane proteins of eukaryotic origin
Title: The membrane insertase Oxa1 is required for efficient import of carrier proteins into mitochondria.

the close proximity of Oxa1 to ribosomes is not only used to improve membrane insertion but is also critical for the productive assembly of the subunits of the cytochrome c oxidase.
Title: Oxa1-ribosome complexes coordinate the assembly of cytochrome C oxidase in mitochondria.

Oxa1 behaves as a pore-forming translocase that is regulated in a membrane potential and substrate-dependent manner
Title: The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers.

Findings show that the distribution of Oxa1 within the inner membrane is dynamic and adapts to different physiological needs.
Title: The inner-mitochondrial distribution of Oxa1 depends on the growth conditions and on the availability of substrates.

The following OXA1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the OXA1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSi05649	NM_001179044.1 Latest version!	Saccharomyces cerevisiae S288C membrane insertase OXA1 (OXA1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

OXA1 ( NM_001179044.1 ) cDNA ORF clone, Saccharomyces cerevisiae S288C -> NP_011081.1 Saccharomyces cerevisiae S288C membrane insertase OXA1 (OXA1), partial mRNA.

Price & Availability↑

CloneID	OSi05649
Clone ID Related Accession (Same CDS sequence)	NM_001179044.1
Accession Version	NM_001179044.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Saccharomyces cerevisiae S288C
Product	membrane insertase OXA1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends.

ATGTTCAAAC TCACCTCTCG ACTCGTCACG TCAAGGTTTG CTGCCTCTTC CAGACTGGCC 
ACCGCTCGAA CCATAGTATT GCCCCGGCCC CATCCGTCAT GGATCTCTTT TCAGGCCAAA 
AGATTTAATT CGACGGGCCC AAATGCCAAC GATGTCTCGG AAATCCAAAC CCAGTTGCCT 
TCCATCGATG AATTAACCTC TTCAGCTCCT TCTCTTTCCG CTTCTACTTC GGACCTTATC 
GCTAACACGA CCCAAACAGT GGGCGAGTTG TCCTCCCATA TAGGGTACTT AAATAGCATT 
GGCCTGGCCC AAACCTGGTA CTGGCCCTCG GACATTATCC AACACGTCTT GGAGGCCGTT 
CATGTTTACT CTGGGTTGCC TTGGTGGGGA ACTATCGCGG CCACCACCAT CCTCATTCGA 
TGCCTGATGT TTCCCCTCTA TGTCAAGTCC TCTGATACTG TTGCTAGAAA TTCCCATATC 
AAGCCCGAGC TGGACGCCTT GAATAATAAG CTAATGTCCA CTACAGATTT GCAACAAGGT 
CAGCTAGTCG CCATGCAAAG GAAAAAACTG CTCTCCTCGC ACGGCATTAA GAACAGATGG 
CTGGCCGCAC CCATGCTACA AATTCCAATC GCCCTTGGGT TTTTCAACGC ATTGAGACAC 
ATGGCTAACT ACCCAGTAGA TGGGTTCGCT AATCAAGGTG TCGCTTGGTT TACAGACTTG 
ACTCAAGCAG ACCCTTACTT AGGTTTGCAA GTAATCACTG CCGCTGTGTT CATCTCATTT 
ACAAGGCTGG GGGGTGAGAC TGGTGCTCAA CAATTCAGTT CTCCCATGAA GCGTCTTTTC 
ACTATTCTAC CGATCATTTC TATACCGGCC ACAATGAACT TATCGTCCGC TGTGGTCCTC 
TACTTTGCCT TTAATGGTGC CTTCTCCGTC CTACAGACAA TGATTTTGAG AAACAAATGG 
GTTCGTTCGA AACTGAAGAT AACAGAAGTA GCTAAACCAA GGACTCCTAT CGCTGGCGCT 
TCCCCCACAG AGAACATGGG CATCTTCCAA TCATTAAAAC ATAACATTCA AAAGGCAAGA 
GATCAGGCGG AAAGAAGGCA ATTGATGCAA GATAATGAGA AGAAGTTACA AGAAAGCTTC 
AAGGAGAAGA GGCAGAATTC CAAAATCAAA ATTGTTCACA AATCAAACTT CATTAATAAC 
AAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_011081.1
CDS	1..1209
Translation	MFKLTSRLVTSRFAASSRLATARTIVLPRPHPSWISFQAKRFNSTGPNANDVSEIQTQLPSIDELTSSAPSLSASTSDLIANTTQTVGELSSHIGYLNSIGLAQTWYWPSDIIQHVLEAVHVYSGLPWWGTIAATTILIRCLMFPLYVKSSDTVARNSHIKPELDALNNKLMSTTDLQQGQLVAMQRKKLLSSHGIKNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAAVFISFTRLGGETGAQQFSSPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMILRNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKHNIQKARDQAERRQLMQDNEKKLQESFKEKRQNSKIKIVHKSNFINNKK

Target ORF information:

RefSeq Version	NM_001179044.1
Organism	Saccharomyces cerevisiae S288C
Definition	Saccharomyces cerevisiae S288C membrane insertase OXA1 (OXA1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001179044.1

ORF Insert Sequence:

ATGTTCAAAC TCACCTCTCG ACTCGTCACG TCAAGGTTTG CTGCCTCTTC CAGACTGGCC 
ACCGCTCGAA CCATAGTATT GCCCCGGCCC CATCCGTCAT GGATCTCTTT TCAGGCCAAA 
AGATTTAATT CGACGGGCCC AAATGCCAAC GATGTCTCGG AAATCCAAAC CCAGTTGCCT 
TCCATCGATG AATTAACCTC TTCAGCTCCT TCTCTTTCCG CTTCTACTTC GGACCTTATC 
GCTAACACGA CCCAAACAGT GGGCGAGTTG TCCTCCCATA TAGGGTACTT AAATAGCATT 
GGCCTGGCCC AAACCTGGTA CTGGCCCTCG GACATTATCC AACACGTCTT GGAGGCCGTT 
CATGTTTACT CTGGGTTGCC TTGGTGGGGA ACTATCGCGG CCACCACCAT CCTCATTCGA 
TGCCTGATGT TTCCCCTCTA TGTCAAGTCC TCTGATACTG TTGCTAGAAA TTCCCATATC 
AAGCCCGAGC TGGACGCCTT GAATAATAAG CTAATGTCCA CTACAGATTT GCAACAAGGT 
CAGCTAGTCG CCATGCAAAG GAAAAAACTG CTCTCCTCGC ACGGCATTAA GAACAGATGG 
CTGGCCGCAC CCATGCTACA AATTCCAATC GCCCTTGGGT TTTTCAACGC ATTGAGACAC 
ATGGCTAACT ACCCAGTAGA TGGGTTCGCT AATCAAGGTG TCGCTTGGTT TACAGACTTG 
ACTCAAGCAG ACCCTTACTT AGGTTTGCAA GTAATCACTG CCGCTGTGTT CATCTCATTT 
ACAAGGCTGG GGGGTGAGAC TGGTGCTCAA CAATTCAGTT CTCCCATGAA GCGTCTTTTC 
ACTATTCTAC CGATCATTTC TATACCGGCC ACAATGAACT TATCGTCCGC TGTGGTCCTC 
TACTTTGCCT TTAATGGTGC CTTCTCCGTC CTACAGACAA TGATTTTGAG AAACAAATGG 
GTTCGTTCGA AACTGAAGAT AACAGAAGTA GCTAAACCAA GGACTCCTAT CGCTGGCGCT 
TCCCCCACAG AGAACATGGG CATCTTCCAA TCATTAAAAC ATAACATTCA AAAGGCAAGA 
GATCAGGCGG AAAGAAGGCA ATTGATGCAA GATAATGAGA AGAAGTTACA AGAAAGCTTC 
AAGGAGAAGA GGCAGAATTC CAAAATCAAA ATTGTTCACA AATCAAACTT CATTAATAAC 
AAAAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Nature387(6632 Suppl)78-81(1997 May)
Dietrich FS,Mulligan J,Hennessy K,Yelton MA,Allen E,Araujo R,Aviles E,Berno A,Brennan T,Carpenter J,Chen E,Cherry JM,Chung E,Duncan M,Guzman E,Hartzell G,Hunicke-Smith S,Hyman RW,Kayser A,Komp C,Lashkari D,Lew H,Lin D,Mosedale D,Davis RW

Life with 6000 genes.
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Goffeau A,Barrell BG,Bussey H,Davis RW,Dujon B,Feldmann H,Galibert F,Hoheisel JD,Jacq C,Johnston M,Louis EJ,Mewes HW,Murakami Y,Philippsen P,Tettelin H,Oliver SG

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OXA1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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