Gene Symbol | CIN8 |
Entrez Gene ID | 856648 |
Full Name | kinesin motor protein CIN8 |
Synonyms | KSL2,SDS15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CIN8 cDNA ORF clone
Gene Symbol | CIN8 |
Entrez Gene ID | 856648 |
Full Name | kinesin motor protein CIN8 |
Synonyms | KSL2,SDS15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178876.1 | NP_010853.2 | kinesin motor protein CIN8 |
Eremothecium gossypii | AGOS_ACR010C | NP_983413.1 |
Saccharomyces cerevisiae (baker's yeast) | CIN8 | NP_010853.2 |
Kluyveromyces lactis | KLLA0D01045g | XP_453117.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Dietrich FS, Mulligan J, Hennessy K, Yelton MA, Allen E, Araujo R, Aviles E, Berno A, Brennan T, Carpenter J, Chen E, Cherry JM, Chung E, Duncan M, Guzman E, Hartzell G, Hunicke-Smith S, Hyman RW, Kayser A, Komp C, Lashkari D, Lew H, Lin D, Mosedale D, Davis RW
Nature387(6632 Suppl)78-81(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Bidirectional Kinesin Cin8 Produce Additive Forces in Both Directions of Movement
Title: Ensembles of Bidirectional Kinesin Cin8 Produce Additive Forces in Both Directions of Movement.
Data suggest that approximately four Cin8 motor domains can bind each alpha/beta-tubulin dimer within microtubule lattice; Cin8 binds microtubules not only at the canonical site, but also one or more separate "non-canonical" sites.
Title: The yeast kinesin-5 Cin8 interacts with the microtubule in a noncanonical manner.
The tail domain is one of the factors that regulate Cin8 directionality.
Title: Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality.
Cin8 mutants lacking critical CDK phosphorylation sites suppress the requirement for Cdc14 and Cdc5 in anaphase spindle elongation.
Title: FEAR-mediated activation of Cdc14 is the limiting step for spindle elongation and anaphase progression.
The deletion mutant cells exhibited reduced midzone-directed motility and efficiency to support spindle elongation, indicating the importance of directionality control for the anaphase function of Cin8.
Title: Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry.
The following CIN8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CIN8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05429 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178876.1 | |
Accession Version | NM_001178876.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3003bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | kinesin motor protein CIN8 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001137). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCCAGCGG AAAACCAAAA TACGGGTCAA GATAGAAGCT CCAACAGCAT CAGTAAAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010853.2 |
CDS | 1..3003 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178876.1 |
1 | ATGCCAGCGG AAAACCAAAA TACGGGTCAA GATAGAAGCT CCAACAGCAT CAGTAAAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V. |
Life with 6000 genes. |