RTT107 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene
Clones
gRNAs

Summary

Gene Symbol	RTT107
Entrez Gene ID	856559
Full Name	Rtt107p
Synonyms	ESC4
Gene Type	protein-coding
Organism	Saccharomyces cerevisiae S288C

mRNA and Protein(s)

mRNA	Protein	Name
NM_001179285.1	NP_012024.1	Rtt107p

Pathways from BioSystems

Homologies

Eremothecium gossypii	AGOS_ADL145C	NP_983951.1
Saccharomyces cerevisiae (baker's yeast)	RTT107	NP_012024.1
Kluyveromyces lactis	KLLA0E15621g	XP_454655.1

Gene Ontology
Bibliography

Related articles in PubMed

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Johnston M, Andrews S, Brinkman R, Cooper J, Ding H, Dover J, Du Z, Favello A, Fulton L, Gattung S
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The scaffold protein Rtt107, which binds the Mus81-Mms4 complex, interacts with Cdc7 and thereby targets Cdc7-Dbf4 and Cdc5 to the complex enabling full Mus81 activation.
Title: Dbf4-dependent kinase and the Rtt107 scaffold promote Mus81-Mms4 resolvase activation during mitosis.

A key function of the Rtt107 BRCT domains for targeting of both itself and its interaction partners to DNA lesions was revealed.
Title: Rtt107 BRCT domains act as a targeting module in the DNA damage response.

Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.
Title: Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.

Rtt107 is a multi-functional scaffold supporting replication progression with partners SUMO, ubiquitin ligase E3, and SLX4.
Title: Rtt107 Is a Multi-functional Scaffold Supporting Replication Progression with Partner SUMO and Ubiquitin Ligases.

The DNA repair scaffold proteins Slx4 and Rtt107 utilize a minimal multi-BRCT-domain module for phosphatase-independent downregulation of DNA damage response signals in yeast.
Title: Dampening DNA damage checkpoint signalling via coordinated BRCT domain interactions.

The following RTT107 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RTT107 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSi05351	NM_001179285.1 Latest version!	Saccharomyces cerevisiae S288C Rtt107p (RTT107), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$629.30 $899.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RTT107 ( NM_001179285.1 ) cDNA ORF clone, Saccharomyces cerevisiae S288C -> NP_012024.1 Saccharomyces cerevisiae S288C Rtt107p (RTT107), partial mRNA.

Price & Availability↑

CloneID	OSi05351
Clone ID Related Accession (Same CDS sequence)	NM_001179285.1
Accession Version	NM_001179285.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3213bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Saccharomyces cerevisiae S288C
Product	Rtt107p
Comment	Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001140). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Veresion :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends.

ATGAGCACAT CACTTCTGTT TGAGCAGCTA AATTTTTTAA TTTTAGTGGC AGCAGAGGCT 
GAGCTTCCCA TCGCTCACTC TACTAGAAAG CTTTTGATGG ATAATTCATG CAATAACTGT 
CAAATATACG AGCTTTATAA CGAAAATTTG AAAGATGTCA AGACGGATAA AGATTGGTTC 
ATGAACAAAT TCGGCCCGCA AACAGTACAT TTTGTCATTA GTAATACAAT CAACTTTCCT 
TTTTATAAGA TAGTTTATTT CGATCTTTTG ATCCCGGTGG TATCACACAC TTGGGTCCAG 
GATTCGGTCA AGACGAAGAG ACATTTGAGG ACAAATATGT ATTCACCTAA CCCATTTCAT 
TTGCTCCGAG ACTGTCAAGT ATATATTTCC AAAAGCTCGT TTAATAAGTG TGAATACATA 
TTATACTCTG ATTTGCTTCA TTTATTAGGA GGCACTTTAG TCAATTACAT CTCAAATAGA 
ACGACGCATG TGATTGTTCA AAGTCCCCAG GACCCGATCA TAGCAACGGT CAGTAAATTG 
ACATTTGGCT CTTTTTCCTC TTCATCGACC AACAAGCACA CCGAAAAGCC TTTGAGAGAG 
TGGAAATTTG TCTATCCAAT ATGGATATTA TATCATTTCA AAATGGCGAA GCCCTTGAAG 
GGCGAGCTTG CTACTTTGTG TGAGCTTGAT ATGCAGGACA CCAGTGAGGA ACAGTTATTC 
GCAAAATGGG AAGAGGTTAT TGGCGATAAG CAGACATCAT CATCGCAGCT TACTCTTCAT 
CCAAACAAAA CTTTATTCAA AAATCACCAC TTTGCTATCT CACCAGATTT AAACTTTTTC 
ACACCTTTGT ATTGGTTTTT GAAAGGATTT ATCGAGGATT TGGACGGCAA AGTAACTCCG 
TTGAGTTTTT CTGACGATCT GAAGTCTGTT TACCAAGCTT TTCCTGATAT TGACTGTTAT 
ATCGGCCACT CTGCTAACTC ACCGATACTA GAAAAAACCA AAAGCATTAA ACCGGAAATT 
CATGTTGGGA ACGTAAGTTG GTTGTTTTAT ATGTTTGCGC TGCAAAAATT TACACCTGTA 
TCGCAATGTA AACTTATTCA CCAACCATTT CATGCGAAAT TATTTACTTC TAAGGAATTA 
ACAGTCGCGT ACACTAATTA TTTCGGCTCC CAAAGGTTTT ATATTCAGAG GTTAGTAGAA 
ATATTAGGAG GACTTAGCAC ACCTGAACTA ACAAGAAAAA ACACACACTT GATCACGAAG 
AGTACAATTG GCAAAAAATT CAAAGTCGCA AAAAAATGGT CACTGGACCC GCAAAATGCC 
ATTATTGTGA CAAATCATAT GTGGTTAGAG CAATGTTATA TGAATAATTC CAAGTTAAAC 
CCCAAAGACA GTAGATTTCA AAATTTTAAA TTGGATGATA ACATGGGATG GAATATCGGC 
CAAATAGGAA TGGATCATTC ATCTCTCCCA ACTCCAAAAA ACCTATCGAT GGTGACTTAC 
GACACGCAAT CCATATCAGA GAAGCCGCCT CCCACAAATG ATCAAATGGA TCAAATTAAC 
GATAACACCA ATGTATTATC AAAGAAAGAT GGTACGCCCA TTAGTAGTTT TGAGAACTCA 
ATTGATGAAA AGATTGACAA ATTACAAAAA ATATCAGGAG AGGTGGCTGT AACCCATTCT 
GGAGATTTAG AACGGAGTTT TGTTTCCAGA CCTTCAAGGG CAAGTTTTCC AGTAGTTGAC 
AGTAAAAAAT CTAATTTACA AAAGAAAGAC TCAAACTCAG ATATTAGTAT GGAAACAGAG 
GTTTTCTGTG AAGGACATGA AAAAAGAGAA GAAAAGGAGT TTACGAAACC TATTACGGAG 
TATGATGCAC CTAAGAAACA AGAAATAAGG GAACAGTCAC GCAAGAAGAA TGACATAGAT 
TATAAAAAAG AAGAGGAAGA AACGGAGCTG CAAGTTCAGC TAGGACAACG AACTAAACGA 
GAGATCAAAA CTTCGAAGAA AAATGAAAAG GAGAAAGAAA CCAATGAATG TCACATTGAA 
GTAGATCAAA TGACGAATGA AAAGCAAGGG GAGGAAAGTA CAGGAAAACT GATTTCTACG 
GAAGACGTCA CTTCTAAAAA AGATACAGAT AAATTCTCGC ATTTGTTTGA AGGATTATCT 
GATAATGATG ATCACATTAA TGACGAAAAA CCGGCAGTTA ATTCCAAATA TACCACACCC 
AAGACGTCTC AAAATATTAC GAGTGGCGTT GATACTCCAA CCACCGCGCA AACGCAAGTT 
TTTATGCCAT CAAGTGGCAA TTCAAGGTTA GCAAAGACAC AAGCTGCGAA GAGATTGCAT 
ACAGATATTG AATCATTAAA TGAATTTCAG AAAAACTTTA AAAGGAAGAG AATTGATAGC 
GAGGAGATTT CATTGTCCCA AGATGTTGAA AGGTCAAATA ATAACAAAGA ACTGGCTACT 
AAAGCGGAAA AGATATTAGC TAGATTTAAT GAACTACCAA ATTATGACCT AAAAGCGGTT 
TGCACCGGTT GTTTCCATGA TGGATTTAAT GAGGTTGACA TCGAAATATT GAACCAACTA 
GGTATAAAAA TTTTTGACAA TATTAAAGAA ACGGATAAAT TGAATTGTAT TTTTGCTCCA 
AAGATTTTGA GAACCGAGAA ATTTTTAAAA AGCTTAAGTT TTGAACCGTT AAAATTCGCA 
TTGAAACCTG AATTTATTAT TGATTTACTG AAACAAATTC ATTCTAAAAA AGATAAACTT 
TCTCAAATAA ATATAAACTT GTTTGATTAT GAGATAAATG GAATTAATGA GAGTATAATA 
TCAAAAACCA AACTACCTAC TAAGGTGTTC GAAAGAGCGA ATATTAGATG CATTAACTTA 
GTCAATGATA TACCGGGTGG TGTAGATACA ATAGGCTCTG TTCTAAAGGC ACATGGTATC 
GAAAAAATCA ACGTTTTACG TAGTAAGAAA TGCACATTTG AAGACATAAT CCCAAATGAC 
GTTTCTAAGC AGGAAAACGG AGGCATTTTT AAATACGTAC TTATCGTCAC CAAAGCTTCA 
CAGGTTAAAA AATTTACCAA ACTGATTAAT GATCGTGATA AAAACGAAAC AATTTTGATT 
GTTGAATGGA ATTGGTGTGT TGAATCAATT TTTCATCTCA ATGTTGATTT TACATCAAAG 
AAAAATGTTT TGTATCAAAA GAAAAATAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_012024.1
CDS	1..3213
Translation	MSTSLLFEQLNFLILVAAEAELPIAHSTRKLLMDNSCNNCQIYELYNENLKDVKTDKDWFMNKFGPQTVHFVISNTINFPFYKIVYFDLLIPVVSHTWVQDSVKTKRHLRTNMYSPNPFHLLRDCQVYISKSSFNKCEYILYSDLLHLLGGTLVNYISNRTTHVIVQSPQDPIIATVSKLTFGSFSSSSTNKHTEKPLREWKFVYPIWILYHFKMAKPLKGELATLCELDMQDTSEEQLFAKWEEVIGDKQTSSSQLTLHPNKTLFKNHHFAISPDLNFFTPLYWFLKGFIEDLDGKVTPLSFSDDLKSVYQAFPDIDCYIGHSANSPILEKTKSIKPEIHVGNVSWLFYMFALQKFTPVSQCKLIHQPFHAKLFTSKELTVAYTNYFGSQRFYIQRLVEILGGLSTPELTRKNTHLITKSTIGKKFKVAKKWSLDPQNAIIVTNHMWLEQCYMNNSKLNPKDSRFQNFKLDDNMGWNIGQIGMDHSSLPTPKNLSMVTYDTQSISEKPPPTNDQMDQINDNTNVLSKKDGTPISSFENSIDEKIDKLQKISGEVAVTHSGDLERSFVSRPSRASFPVVDSKKSNLQKKDSNSDISMETEVFCEGHEKREEKEFTKPITEYDAPKKQEIREQSRKKNDIDYKKEEEETELQVQLGQRTKREIKTSKKNEKEKETNECHIEVDQMTNEKQGEESTGKLISTEDVTSKKDTDKFSHLFEGLSDNDDHINDEKPAVNSKYTTPKTSQNITSGVDTPTTAQTQVFMPSSGNSRLAKTQAAKRLHTDIESLNEFQKNFKRKRIDSEEISLSQDVERSNNNKELATKAEKILARFNELPNYDLKAVCTGCFHDGFNEVDIEILNQLGIKIFDNIKETDKLNCIFAPKILRTEKFLKSLSFEPLKFALKPEFIIDLLKQIHSKKDKLSQININLFDYEINGINESIISKTKLPTKVFERANIRCINLVNDIPGGVDTIGSVLKAHGIEKINVLRSKKCTFEDIIPNDVSKQENGGIFKYVLIVTKASQVKKFTKLINDRDKNETILIVEWNWCVESIFHLNVDFTSKKNVLYQKKNN

Target ORF information:

RefSeq Version	NM_001179285.1
Organism	Saccharomyces cerevisiae S288C
Definition	Saccharomyces cerevisiae S288C Rtt107p (RTT107), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001179285.1

ORF Insert Sequence:

ATGAGCACAT CACTTCTGTT TGAGCAGCTA AATTTTTTAA TTTTAGTGGC AGCAGAGGCT 
GAGCTTCCCA TCGCTCACTC TACTAGAAAG CTTTTGATGG ATAATTCATG CAATAACTGT 
CAAATATACG AGCTTTATAA CGAAAATTTG AAAGATGTCA AGACGGATAA AGATTGGTTC 
ATGAACAAAT TCGGCCCGCA AACAGTACAT TTTGTCATTA GTAATACAAT CAACTTTCCT 
TTTTATAAGA TAGTTTATTT CGATCTTTTG ATCCCGGTGG TATCACACAC TTGGGTCCAG 
GATTCGGTCA AGACGAAGAG ACATTTGAGG ACAAATATGT ATTCACCTAA CCCATTTCAT 
TTGCTCCGAG ACTGTCAAGT ATATATTTCC AAAAGCTCGT TTAATAAGTG TGAATACATA 
TTATACTCTG ATTTGCTTCA TTTATTAGGA GGCACTTTAG TCAATTACAT CTCAAATAGA 
ACGACGCATG TGATTGTTCA AAGTCCCCAG GACCCGATCA TAGCAACGGT CAGTAAATTG 
ACATTTGGCT CTTTTTCCTC TTCATCGACC AACAAGCACA CCGAAAAGCC TTTGAGAGAG 
TGGAAATTTG TCTATCCAAT ATGGATATTA TATCATTTCA AAATGGCGAA GCCCTTGAAG 
GGCGAGCTTG CTACTTTGTG TGAGCTTGAT ATGCAGGACA CCAGTGAGGA ACAGTTATTC 
GCAAAATGGG AAGAGGTTAT TGGCGATAAG CAGACATCAT CATCGCAGCT TACTCTTCAT 
CCAAACAAAA CTTTATTCAA AAATCACCAC TTTGCTATCT CACCAGATTT AAACTTTTTC 
ACACCTTTGT ATTGGTTTTT GAAAGGATTT ATCGAGGATT TGGACGGCAA AGTAACTCCG 
TTGAGTTTTT CTGACGATCT GAAGTCTGTT TACCAAGCTT TTCCTGATAT TGACTGTTAT 
ATCGGCCACT CTGCTAACTC ACCGATACTA GAAAAAACCA AAAGCATTAA ACCGGAAATT 
CATGTTGGGA ACGTAAGTTG GTTGTTTTAT ATGTTTGCGC TGCAAAAATT TACACCTGTA 
TCGCAATGTA AACTTATTCA CCAACCATTT CATGCGAAAT TATTTACTTC TAAGGAATTA 
ACAGTCGCGT ACACTAATTA TTTCGGCTCC CAAAGGTTTT ATATTCAGAG GTTAGTAGAA 
ATATTAGGAG GACTTAGCAC ACCTGAACTA ACAAGAAAAA ACACACACTT GATCACGAAG 
AGTACAATTG GCAAAAAATT CAAAGTCGCA AAAAAATGGT CACTGGACCC GCAAAATGCC 
ATTATTGTGA CAAATCATAT GTGGTTAGAG CAATGTTATA TGAATAATTC CAAGTTAAAC 
CCCAAAGACA GTAGATTTCA AAATTTTAAA TTGGATGATA ACATGGGATG GAATATCGGC 
CAAATAGGAA TGGATCATTC ATCTCTCCCA ACTCCAAAAA ACCTATCGAT GGTGACTTAC 
GACACGCAAT CCATATCAGA GAAGCCGCCT CCCACAAATG ATCAAATGGA TCAAATTAAC 
GATAACACCA ATGTATTATC AAAGAAAGAT GGTACGCCCA TTAGTAGTTT TGAGAACTCA 
ATTGATGAAA AGATTGACAA ATTACAAAAA ATATCAGGAG AGGTGGCTGT AACCCATTCT 
GGAGATTTAG AACGGAGTTT TGTTTCCAGA CCTTCAAGGG CAAGTTTTCC AGTAGTTGAC 
AGTAAAAAAT CTAATTTACA AAAGAAAGAC TCAAACTCAG ATATTAGTAT GGAAACAGAG 
GTTTTCTGTG AAGGACATGA AAAAAGAGAA GAAAAGGAGT TTACGAAACC TATTACGGAG 
TATGATGCAC CTAAGAAACA AGAAATAAGG GAACAGTCAC GCAAGAAGAA TGACATAGAT 
TATAAAAAAG AAGAGGAAGA AACGGAGCTG CAAGTTCAGC TAGGACAACG AACTAAACGA 
GAGATCAAAA CTTCGAAGAA AAATGAAAAG GAGAAAGAAA CCAATGAATG TCACATTGAA 
GTAGATCAAA TGACGAATGA AAAGCAAGGG GAGGAAAGTA CAGGAAAACT GATTTCTACG 
GAAGACGTCA CTTCTAAAAA AGATACAGAT AAATTCTCGC ATTTGTTTGA AGGATTATCT 
GATAATGATG ATCACATTAA TGACGAAAAA CCGGCAGTTA ATTCCAAATA TACCACACCC 
AAGACGTCTC AAAATATTAC GAGTGGCGTT GATACTCCAA CCACCGCGCA AACGCAAGTT 
TTTATGCCAT CAAGTGGCAA TTCAAGGTTA GCAAAGACAC AAGCTGCGAA GAGATTGCAT 
ACAGATATTG AATCATTAAA TGAATTTCAG AAAAACTTTA AAAGGAAGAG AATTGATAGC 
GAGGAGATTT CATTGTCCCA AGATGTTGAA AGGTCAAATA ATAACAAAGA ACTGGCTACT 
AAAGCGGAAA AGATATTAGC TAGATTTAAT GAACTACCAA ATTATGACCT AAAAGCGGTT 
TGCACCGGTT GTTTCCATGA TGGATTTAAT GAGGTTGACA TCGAAATATT GAACCAACTA 
GGTATAAAAA TTTTTGACAA TATTAAAGAA ACGGATAAAT TGAATTGTAT TTTTGCTCCA 
AAGATTTTGA GAACCGAGAA ATTTTTAAAA AGCTTAAGTT TTGAACCGTT AAAATTCGCA 
TTGAAACCTG AATTTATTAT TGATTTACTG AAACAAATTC ATTCTAAAAA AGATAAACTT 
TCTCAAATAA ATATAAACTT GTTTGATTAT GAGATAAATG GAATTAATGA GAGTATAATA 
TCAAAAACCA AACTACCTAC TAAGGTGTTC GAAAGAGCGA ATATTAGATG CATTAACTTA 
GTCAATGATA TACCGGGTGG TGTAGATACA ATAGGCTCTG TTCTAAAGGC ACATGGTATC 
GAAAAAATCA ACGTTTTACG TAGTAAGAAA TGCACATTTG AAGACATAAT CCCAAATGAC 
GTTTCTAAGC AGGAAAACGG AGGCATTTTT AAATACGTAC TTATCGTCAC CAAAGCTTCA 
CAGGTTAAAA AATTTACCAA ACTGATTAAT GATCGTGATA AAAACGAAAC AATTTTGATT 
GTTGAATGGA ATTGGTGTGT TGAATCAATT TTTCATCTCA ATGTTGATTT TACATCAAAG 
AAAAATGTTT TGTATCAAAA GAAAAATAAC TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Life with 6000 genes.
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Goffeau A,Barrell BG,Bussey H,Davis RW,Dujon B,Feldmann H,Galibert F,Hoheisel JD,Jacq C,Johnston M,Louis EJ,Mewes HW,Murakami Y,Philippsen P,Tettelin H,Oliver SG

Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
Science (New York, N.Y.)265(5181)2077-82(1994 Sep)
Johnston M,Andrews S,Brinkman R,Cooper J,Ding H,Dover J,Du Z,Favello A,Fulton L,Gattung S

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RTT107 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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