Gene Symbol | DPB2 |
Entrez Gene ID | 856305 |
Full Name | DNA polymerase epsilon noncatalytic subunit |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » DPB2 cDNA ORF clone
Gene Symbol | DPB2 |
Entrez Gene ID | 856305 |
Full Name | DNA polymerase epsilon noncatalytic subunit |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184272.1 | NP_015501.2 | DNA polymerase epsilon noncatalytic subunit |
Kluyveromyces lactis | KLLA0E04775g | XP_454161.1 |
Schizosaccharomyces pombe (fission yeast) | dpb2 | NP_596521.1 |
Neurospora crassa | NCU10155 | XP_958288.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_07222 | XP_003715439.1 |
Saccharomyces cerevisiae (baker's yeast) | DPB2 | NP_015501.2 |
Eremothecium gossypii | AGOS_AEL267C | NP_984593.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
dpb2-103 mutant cells progress through S phase faster than wild-type cells. Nrm1-dependent branch of the checkpoint is impaired in dpb2-103 cells.
Title: Mutations in the Non-Catalytic Subunit Dpb2 of DNA Polymerase Epsilon Affect the Nrm1 Branch of the DNA Replication Checkpoint.
The presence of the dpb2-100 mutant significantly decreases the interaction of Dpb2p with Psf1p and Psf3p.
Title: Fidelity consequences of the impaired interaction between DNA polymerase epsilon and the GINS complex.
Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome.
Title: Dpb2 integrates the leading-strand DNA polymerase into the eukaryotic replisome.
Authors propose that the essential function of Dpb2 is separate from the enzymatic activity of Pol epsilon in S. cerevisiae and that Dpb2 depends on a distinct domain at the very C-terminal end of the protein to physically interact with Pol2.
Title: The C-terminus of Dpb2 is required for interaction with Pol2 and for cell viability.
This DNA polymerase subunit other than those housing the DNA polymerase and 3' --> 5' exonuclease is essential in controlling the level of spontaneous mutagenesis and genetic stability in yeast cells.
Title: Dpb2p, a noncatalytic subunit of DNA polymerase epsilon, contributes to the fidelity of DNA replication in Saccharomyces cerevisiae.
The following DPB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DPB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi05121 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184272.1 | |
Accession Version | NM_001184272.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2070bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | DNA polymerase epsilon noncatalytic subunit | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTTGGCT CTGGGAATGT TCTGCCTGTT AAAATTCAGC CTCCGCTGCT TAGGCCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015501.2 |
CDS | 1..2070 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184272.1 |
1 | ATGTTTGGCT CTGGGAATGT TCTGCCTGTT AAAATTCAGC CTCCGCTGCT TAGGCCACTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |