Gene Symbol | PHO85 |
Entrez Gene ID | 856076 |
Full Name | cyclin-dependent serine/threonine-protein kinase PHO85 |
Synonyms | LDB15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PHO85 cDNA ORF clone
Gene Symbol | PHO85 |
Entrez Gene ID | 856076 |
Full Name | cyclin-dependent serine/threonine-protein kinase PHO85 |
Synonyms | LDB15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183845.1 | NP_015294.1 | cyclin-dependent serine/threonine-protein kinase PHO85 |
Rattus norvegicus (Norway rat) | Cdk5 | NP_543161.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005772 | XP_315787.4 |
Saccharomyces cerevisiae (baker's yeast) | PHO85 | NP_015294.1 |
Neurospora crassa | NCU07580 | XP_958274.1 |
Xenopus tropicalis (tropical clawed frog) | cdk5 | NP_001072776.1 |
Homo sapiens (human) | CDK5 | NP_004926.1 |
CDK5 | XP_001102523.1 | |
Canis lupus familiaris (dog) | CDK5 | XP_005629809.1 |
Bos taurus (cattle) | CDK5 | NP_776442.1 |
Gallus gallus (chicken) | CDK5 | NP_001129258.1 |
Eremothecium gossypii | AGOS_AGL242C | NP_986425.2 |
Pan troglodytes (chimpanzee) | CDK5 | XP_519523.2 |
Mus musculus (house mouse) | Cdk5 | NP_031694.1 |
Danio rerio (zebrafish) | cdk5 | NP_571794.1 |
Drosophila melanogaster (fruit fly) | Cdk5 | NP_477080.1 |
Caenorhabditis elegans (roundworm) | cdk-5 | NP_499783.1 |
Kluyveromyces lactis | KLLA0D11990g | XP_453596.1 |
Schizosaccharomyces pombe (fission yeast) | pef1 | NP_587921.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_04660 | XP_003713655.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Pho85/CDK5 provides protection against hyperosmotic stress and acts before long-term adaptation provided by Hog1. This protection requires the vacuolar/endolysosomal signaling lipid PI3,5P2 We show that Pho85/CDK5 directly phosphorylates and positively regulates the PI3P-5 kinase Fab1/PIKfyve complex and provide evidence that this regulation is conserved in mammalian cells.
Title: Early protection to stress mediated by CDK-dependent PI3,5P
Pho85 and Pho4 regulated CLN2 expression under alkaline condition.
Title: The regulators of yeast PHO system participate in the transcriptional regulation of G1 cyclin under alkaline stress conditions.
with Srb10 clearing mostly inactive Gcn4 molecules at the promoter that are enriched for sumoylation of the activation domain, and Pho85 clearing molecules unbound to the UAS that include both fully functional and inactive Gcn4 species.
Title: Accumulation of a threonine biosynthetic intermediate attenuates general amino acid control by accelerating degradation of Gcn4 via Pho85 and Cdk8.
phosphorylations by protein kinase C and Pho85p-Pho80p protein kinase regulate Pah1p phosphatidate phosphatase abundance in Saccharomyces cerevisiae
Title: Cross-talk phosphorylations by protein kinase C and Pho85p-Pho80p protein kinase regulate Pah1p phosphatidate phosphatase abundance in Saccharomyces cerevisiae.
Comparison between Pho85-Pcl10, phosphorylated CDK2-cyclin A, and CDK5-p25 complexes reveals the convergent structural characteristics necessary for full kinase activity and the variations in the substrate recognition mechanism.
Title: New structural insights into phosphorylation-free mechanism for full cyclin-dependent kinase (CDK)-cyclin activity and substrate recognition.
The following PHO85 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PHO85 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04934 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183845.1 | |
Accession Version | NM_001183845.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 918bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cyclin-dependent serine/threonine-protein kinase PHO85 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTTCTT CTTCACAATT TAAGCAGTTA GAAAAGCTTG GCAATGGTAC GTATGCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015294.1 |
CDS | 1..918 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183845.1 |
1 | ATGTCTTCTT CTTCACAATT TAAGCAGTTA GAAAAGCTTG GCAATGGTAC GTATGCCACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |