Gene Symbol | MUK1 |
Entrez Gene ID | 856035 |
Full Name | guanine nucleotide exchange factor MUK1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MUK1 cDNA ORF clone
Gene Symbol | MUK1 |
Entrez Gene ID | 856035 |
Full Name | guanine nucleotide exchange factor MUK1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183884.1 | NP_015255.1 | guanine nucleotide exchange factor MUK1 |
Saccharomyces cerevisiae (baker's yeast) | MUK1 | NP_015255.1 |
Kluyveromyces lactis | KLLA0E23321g | XP_455004.1 |
Eremothecium gossypii | AGOS_AEL239W | NP_984622.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Muk1 lacks ubiquitin-binding motifs, but its fusion to the Vps9 CUE domain allows Muk1 to rescue endosome morphology & cargo trafficking that result from loss of Vps9 function caused by dysfunction of endosomal sorting complexes required for transport
Title: Ubiquitin binding by the CUE domain promotes endosomal localization of the Rab5 GEF Vps9.
Novel physical interactions between retromer and the Saccharomyces cerevisiae VPS9-domain Rab5-family guanine nucleotide exchange factors Muk1 and Vps9 promote their recruitment to endosomes.
Title: Rab5-family guanine nucleotide exchange factors bind retromer and promote its recruitment to endosomes.
Data indicate that Cells lacking both Vps9 and Muk1 closely phenocopy double and triple knock-out strains lacking Rab5 paralogs.
Title: Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast.
The following MUK1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MUK1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04899 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183884.1 | |
Accession Version | NM_001183884.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1839bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | guanine nucleotide exchange factor MUK1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCTAGAC AATTATTCAC TCCTCCGATA ACCAATCCAA GGTTTGACCC TAATCAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015255.1 |
CDS | 1..1839 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183884.1 |
1 | ATGGCTAGAC AATTATTCAC TCCTCCGATA ACCAATCCAA GGTTTGACCC TAATCAATCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |