Gene Symbol | ELP3 |
Entrez Gene ID | 856019 |
Full Name | Elongator subunit ELP3 |
Synonyms | HPA1,KAT9,KTI8,TOT3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » ELP3 cDNA ORF clone
Gene Symbol | ELP3 |
Entrez Gene ID | 856019 |
Full Name | Elongator subunit ELP3 |
Synonyms | HPA1,KAT9,KTI8,TOT3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183900.1 | NP_015239.1 | Elongator subunit ELP3 |
ELP3 | XP_001110226.1 | |
Xenopus tropicalis (tropical clawed frog) | elp3 | NP_001001215.1 |
Rattus norvegicus (Norway rat) | LOC100362548 | XP_002728336.1 |
Eremothecium gossypii | AGOS_AGR201C | NP_986867.1 |
Schizosaccharomyces pombe (fission yeast) | elp3 | NP_594862.1 |
Oryza sativa (rice) | Os04g0484900 | NP_001053128.1 |
Pan troglodytes (chimpanzee) | ELP3 | XP_001165532.1 |
Mus musculus (house mouse) | Elp3 | NP_083087.1 |
Gallus gallus (chicken) | ELP3 | NP_001034382.1 |
Drosophila melanogaster (fruit fly) | Elp3 | NP_608834.1 |
Danio rerio (zebrafish) | elp3 | NP_001014344.2 |
Caenorhabditis elegans (roundworm) | elpc-3 | NP_506055.2 |
Saccharomyces cerevisiae (baker's yeast) | ELP3 | NP_015239.1 |
Homo sapiens (human) | ELP3 | NP_060561.3 |
Canis lupus familiaris (dog) | ELP3 | XP_534563.3 |
Bos taurus (cattle) | ELP3 | NP_001124234.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008300 | XP_317165.4 |
Kluyveromyces lactis | KLLA0E23937g | XP_455030.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_05481 | XP_003710346.1 |
Neurospora crassa | NCU01229 | XP_961595.1 |
Arabidopsis thaliana (thale cress) | ELO3 | NP_568725.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
both Elp3-induced acetylation and Hos2-induced deacetylation influence the nucleosome positions in the promoters of 24 genes
Title: Comparative studies of genome-wide maps of nucleosomes between deletion mutants of elp3 and hos2 genes of Saccharomyces cerevisiae.
We present our working model in which Elp3/Gcn5 and the APC work together to facilitate passage through mitosis and G(1). To progress into S, we propose that at least Gcn5 must then be targeted for degradation in an APC-dependent fashion.
Title: The Saccharomyces cerevisiae anaphase-promoting complex interacts with multiple histone-modifying enzymes to regulate cell cycle progression.
Results conclude that yeast and plant Elongator (elp3/ELO3) share tRNA modification roles and propose that this function might be conserved in Elongator from all eukaryotic kingdoms of life.
Title: Elongator function in tRNA wobble uridine modification is conserved between yeast and plants.
report an interaction between the Elongator histone acetyltransferase and the proliferating cell nuclear antigen. Cells lacking Elp3 and are sensitive to the DNA replication inhibitor hydroxyurea and the damaging agent methyl methanesulfonate.
Title: The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents.
the Elp3 FeS cluster is essential for normal Elongator function in vivo primarily as a structural, rather than catalytic, domain.
Title: An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator.
The following ELP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04885 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183900.1 | |
Accession Version | NM_001183900.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1674bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Elongator subunit ELP3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCTCGTC ATGGAAAAGG CCCAAAAACT AACAAAAAAA AGCTAGCACC TGAAAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015239.1 |
CDS | 1..1674 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183900.1 |
1 | ATGGCTCGTC ATGGAAAAGG CCCAAAAACT AACAAAAAAA AGCTAGCACC TGAAAAGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |