Gene Symbol | IPL1 |
Entrez Gene ID | 855892 |
Full Name | aurora kinase |
Synonyms | PAC15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » IPL1 cDNA ORF clone
Gene Symbol | IPL1 |
Entrez Gene ID | 855892 |
Full Name | aurora kinase |
Synonyms | PAC15 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184023.1 | NP_015115.1 | aurora kinase |
Homo sapiens (human) | AURKB | NP_001271455.1 |
Canis lupus familiaris (dog) | AURKB | XP_005620070.1 |
Bos taurus (cattle) | AURKB | NP_898907.2 |
Danio rerio (zebrafish) | aurkb | NP_997731.1 |
Eremothecium gossypii | AGOS_AFL101C | NP_985449.1 |
Schizosaccharomyces pombe (fission yeast) | ark1 | NP_001018849.1 |
AURKB | XP_001118154.2 | |
Mus musculus (house mouse) | Aurkb | NP_035626.1 |
Rattus norvegicus (Norway rat) | Aurkb | NP_446201.1 |
Saccharomyces cerevisiae (baker's yeast) | IPL1 | NP_015115.1 |
Kluyveromyces lactis | KLLA0B02332g | XP_451635.1 |
Neurospora crassa | NCU00108 | XP_957232.1 |
Pan troglodytes (chimpanzee) | AURKB | XP_511856.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_00479 | XP_003718583.1 |
Xenopus tropicalis (tropical clawed frog) | aurkb | NP_001016859.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Decatenation and condensation defects lead to spindle stabilization during cytokinesis, allowing bridge detection by Aurora B.
Title: The Aurora-B-dependent NoCut checkpoint prevents?damage of anaphase bridges after DNA replication?stress.
Shedding is regulated by the conserved protein kinase Ipl1/Aurora-B and promotes the subsequent assembly of a kinetochore.
Title: Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae.
increase in Aurora B activity causes premature collapse of the mitotic spindle by promoting instability of the spindle midzone.
Title: Increased Aurora B activity causes continuous disruption of kinetochore-microtubule attachments and spindle instability.
Ipl1-dependent phosphorylation of Sli15 therefore inhibits its association with microtubules both in vivo and in vitro and may negatively regulate the tension checkpoint mechanism.
Title: Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.
a novel and unexpected role for Aurora kinase in preventing the formation of spindles by Clb5-CDK (S-CDK) during meiotic prophase I
Title: Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis.
The following IPL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IPL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04768 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184023.1 | |
Accession Version | NM_001184023.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | aurora kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCAACGCA ATAGTTTAGT AAATATCAAA CTAAACGCTA ATTCGCCATC GAAAAAGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015115.1 |
CDS | 1..1104 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184023.1 |
1 | ATGCAACGCA ATAGTTTAGT AAATATCAAA CTAAACGCTA ATTCGCCATC GAAAAAGACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |