Gene Symbol | FUM1 |
Entrez Gene ID | 855866 |
Full Name | fumarase FUM1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » FUM1 cDNA ORF clone
Gene Symbol | FUM1 |
Entrez Gene ID | 855866 |
Full Name | fumarase FUM1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184076.1 | NP_015061.1 | fumarase FUM1 |
Canis lupus familiaris (dog) | FH | XP_537215.1 |
Mus musculus (house mouse) | Fh1 | NP_034339.2 |
Danio rerio (zebrafish) | fh | NP_957257.1 |
Drosophila melanogaster (fruit fly) | l(1)G0255 | NP_572339.1 |
Arabidopsis thaliana (thale cress) | FUM2 | NP_199908.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100491219 | XP_002935862.2 |
FH | XP_001094968.1 | |
Magnaporthe oryzae (rice blast fungus) | MGG_17962 | XP_003720956.1 |
Pan troglodytes (chimpanzee) | FH | XP_001159979.1 |
Rattus norvegicus (Norway rat) | Fh | NP_058701.2 |
Saccharomyces cerevisiae (baker's yeast) | FUM1 | NP_015061.1 |
Kluyveromyces lactis | KLLA0D00902g | XP_453112.1 |
Eremothecium gossypii | AGOS_ACR013C | NP_983416.2 |
Schizosaccharomyces pombe (fission yeast) | fum1 | NP_588397.3 |
Arabidopsis thaliana (thale cress) | FUM1 | NP_001078075.1 |
Homo sapiens (human) | FH | NP_000134.2 |
Bos taurus (cattle) | FH | NP_001069271.1 |
Gallus gallus (chicken) | FH | NP_001006382.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001884 | XP_321179.4 |
Caenorhabditis elegans (roundworm) | fum-1 | NP_498642.1 |
Neurospora crassa | NCU10008 | XP_959454.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that fumarase and fumaric acid are critical elements of the DNA damage response, which underlies the tumor suppressor role of fumarase in human cells and which is most probably HIF independent.
Title: Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.
Dual distribution of fumarase in mitochondria and cytosol depends on an enzymatically active Cit2.
Title: Dual localization of fumarase is dependent on the integrity of the glyoxylate shunt.
cytosolic exposure of the fumarase nascent chain depends on both translocation and translation rates
Title: Translation-coupled translocation of yeast fumarase into mitochondria in vivo.
extramitochondrial presence of yeast fumarase is mainly caused by the poor mitochondrial targeting characteristics of its mitochondrial targeting sequence
Title: Mitochondrial import of human and yeast fumarase in live mammalian cells: retrograde translocation of the yeast enzyme is mainly caused by its poor targeting sequence.
The following FUM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FUM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04743 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184076.1 | |
Accession Version | NM_001184076.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1467bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | fumarase FUM1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTTGAGAT TTACCAATTG TAGTTGCAAG ACTTTCGTAA AATCGTCATA TAAGCTTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015061.1 |
CDS | 1..1467 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184076.1 |
1 | ATGTTGAGAT TTACCAATTG TAGTTGCAAG ACTTTCGTAA AATCGTCATA TAAGCTTAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |