Gene Symbol | HSP82 |
Entrez Gene ID | 855836 |
Full Name | Hsp90 family chaperone HSP82 |
Synonyms | HSP90 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » HSP82 cDNA ORF clone
Gene Symbol | HSP82 |
Entrez Gene ID | 855836 |
Full Name | Hsp90 family chaperone HSP82 |
Synonyms | HSP90 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001184054.1 | NP_015084.1 | Hsp90 family chaperone HSP82 |
Drosophila melanogaster (fruit fly) | Hsp83 | NP_001261362.1 |
Arabidopsis thaliana (thale cress) | HSP90.1 | NP_200076.1 |
Mus musculus (house mouse) | Hsp90ab1 | NP_032328.2 |
Gallus gallus (chicken) | HSP90AB1 | NP_996842.1 |
Saccharomyces cerevisiae (baker's yeast) | HSP82 | NP_015084.1 |
Kluyveromyces lactis | KLLA0D12958g | XP_453640.1 |
Schizosaccharomyces pombe (fission yeast) | hsp90 | NP_594365.1 |
Canis lupus familiaris (dog) | HSP90AB1 | XP_532154.4 |
Bos taurus (cattle) | HSP90AB1 | NP_001073105.1 |
Danio rerio (zebrafish) | hsp90ab1 | NP_571385.2 |
Caenorhabditis elegans (roundworm) | daf-21 | NP_506626.1 |
Neurospora crassa | NCU04142 | XP_961298.1 |
Oryza sativa (rice) | Os08g0500700 | NP_001062159.1 |
Homo sapiens (human) | HSP90AB1 | NP_001258898.1 |
Pan troglodytes (chimpanzee) | HSP90AB1 | XP_003311385.1 |
HSP90AB1 | XP_001099135.2 | |
Rattus norvegicus (Norway rat) | Hsp90ab1 | NP_001004082.3 |
Anopheles gambiae (African malaria mosquito) | HSP83_ANOGA | XP_308800.3 |
Eremothecium gossypii | AGOS_AFL148C | NP_985402.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06759 | XP_003709473.1 |
Xenopus tropicalis (tropical clawed frog) | hsp90ab1 | NP_001025655.1 |
Saccharomyces cerevisiae (baker's yeast) | HSC82 | NP_013911.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
Bussey H, Storms RK, Ahmed A, Albermann K, Allen E, Ansorge W, Araujo R, Aparicio A, Barrell B, Badcock K, Benes V, Botstein D, Bowman S, Br?ckner M, Carpenter J, Cherry JM, Chung E, Churcher C, Coster F, Davis K, Davis RW, Dietrich FS, Delius H, DiPaolo T, Hani J
Nature387(6632 Suppl)103-5(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
A chemical compound inhibiting the Aha1-Hsp90 chaperone complex
Title: A chemical compound inhibiting the Aha1-Hsp90 chaperone complex.
Report the importance of Hsp90/Sgt1 system in controlling cell plasticity.
Title: The Plasticity of the Hsp90 Co-chaperone System.
Using crosslinking, hydrogen exchange mass spectrometry, and fluorescence experiments, we demonstrate here that the N-terminal domain of Hsp90 rotates by approximately 180 degrees as compared to the crystal structure of yeast Hsp90 in complex with Sba1 and AMPPNP.
Title: Large Rotation of the N-terminal Domain of Hsp90 Is Important for Interaction with Some but Not All Client Proteins.
This study used Hsp90 mutants that modulate ATPase activity and biological function as probes to address the importance of conformational cycling for Hsp90 activity. The study found no correlation between the speed of ATP turnover and the in vivo activity of Hsp90: some mutants with almost normal ATPase activity were lethal, and some mutants with lower or undetectable ATPase activity were viable.
Title: Importance of cycle timing for the function of the molecular chaperone Hsp90.
The impact of different allosteric modulators on the stability, structural and internal dynamics properties of Hsp90 closed state was used to develop a quantitative model relating Hsp90 activation to the presence of a certain compound, using information on the dynamic adaptation of protein conformations to the presence of the ligand, which allows the capture of conformational states relevant in the activation process.
Title: Molecular Dynamics Simulations Reveal the Mechanisms of Allosteric Activation of Hsp90 by Designed Ligands.
The following HSP82 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HSP82 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04718 | |
Clone ID Related Accession (Same CDS sequence) | NM_001184054.1 | |
Accession Version | NM_001184054.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2130bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Hsp90 family chaperone HSP82 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001148). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCTAGTG AAACTTTTGA ATTTCAAGCT GAAATTACTC AGTTGATGAG TTTGATCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_015084.1 |
CDS | 1..2130 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001184054.1 |
1 | ATGGCTAGTG AAACTTTTGA ATTTCAAGCT GAAATTACTC AGTTGATGAG TTTGATCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. |
Life with 6000 genes. |