Gene Symbol | RFA2 |
Entrez Gene ID | 855404 |
Full Name | Rfa2p |
Synonyms | BUF1,RPA2,RPA32 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RFA2 cDNA ORF clone
Gene Symbol | RFA2 |
Entrez Gene ID | 855404 |
Full Name | Rfa2p |
Synonyms | BUF1,RPA2,RPA32 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183150.1 | NP_014087.1 | Rfa2p |
Drosophila melanogaster (fruit fly) | RPA2 | NP_610077.1 |
Saccharomyces cerevisiae (baker's yeast) | RFA2 | NP_014087.1 |
Schizosaccharomyces pombe (fission yeast) | ssb2 | NP_588227.2 |
Oryza sativa (rice) | Os02g0633400 | NP_001047510.1 |
Pan troglodytes (chimpanzee) | RPA2 | XP_003307967.1 |
Bos taurus (cattle) | RPA2 | NP_001039449.1 |
Neurospora crassa | NCU07717 | XP_961967.1 |
Oryza sativa (rice) | Os02g0829100 | NP_001048604.1 |
Kluyveromyces lactis | KLLA0E07371g | XP_002999398.1 |
RPA2 | XP_002802309.1 | |
Canis lupus familiaris (dog) | RPA2 | XP_003638988.1 |
Mus musculus (house mouse) | Rpa2 | NP_035414.3 |
Rattus norvegicus (Norway rat) | Rpa2 | NP_067593.1 |
Eremothecium gossypii | AGOS_ADL176W | NP_983920.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_07124 | XP_003715317.1 |
Arabidopsis thaliana (thale cress) | RPA2 | NP_565571.1 |
Arabidopsis thaliana (thale cress) | RPA32B | NP_566188.1 |
Homo sapiens (human) | RPA2 | NP_002937.1 |
Gallus gallus (chicken) | RPA2 | NP_001026063.1 |
Danio rerio (zebrafish) | rpa2 | NP_571786.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008332 | XP_317127.3 |
Xenopus tropicalis (tropical clawed frog) | rpa2 | NP_001006795.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
Philippsen P, Kleine K, P?hlmann R, D?sterh?ft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K, Altmann R, Andr? B, Baladron V, Ballesta JP, B?cam AM, Beinhauer J, Boskovic J, Buitrago MJ, Bussereau F, Coster F, Crouzet M, D'Angelo M, Dal Pero F, De Antoni A, Del Rey F, Doignon F, Domdey H, Dubois E, Fiedler T, Fleig U, Floeth M, Fritz C, Gaillardin C, Garcia-Cantalejo JM, Glansdorff NN, Goffeau A, Gueldener U, Herbert C, Heumann K, Heuss-Neitzel D, Hilbert H, Hinni K, Iraqui Houssaini I, Jacquet M, Jimenez A, Jonniaux JL, Karpfinger L, Lanfranchi G, Lepingle A, Levesque H, Lyck R, Maftahi M, Mallet L, Maurer KC, Messenguy F, Mewes HW, M?sti D, Nasr F, Nicaud JM, Niedenthal RK, Pandolfo D, Pi?rard A, Piravandi E, Planta RJ, Pohl TM, Purnelle B, Rebischung C, Remacha M, Revuelta JL, Rinke M, Saiz JE, Sartorello F, Scherens B, Sen-Gupta M, Soler-Mira A, Urbanus JH, Valle G, Van Dyck L, Verhasselt P, Vierendeels F, Vissers S, Voet M, Volckaert G, Wach A, Wambutt R, Wedler H, Zollner A, Hani J
Nature387(6632 Suppl)93-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Post-translational modification of the Rfa2 N-terminus is not required for cells to deal with DNA damage; however, it might influence whether cells proceed into M-phase in the continued presence of unrepaired DNA lesions.
Title: The DNA damage response and checkpoint adaptation in Saccharomyces cerevisiae: distinct roles for the replication protein A2 (Rfa2) N-terminus.
Results show that DNA damage response at eroded telomeres is characterized by the recruitment of Cdc13, replication protein A, DNA damage checkpoint proteins and the DNA repair protein Rad52 into a single focus.
Title: The DNA damage response at eroded telomeres and tethering to the nuclear pore complex.
Results suggests that RPA2 is necessary for structural integrity and may also be needed for intra- and/or inter-protein interactions.
Title: Essential functions of the 32 kDa subunit of yeast replication protein A.
Rfa2 serine 27 (S27) is required for Ime2-dependent Rfa2 phosphorylation in vivo.
Title: Mechanistic insight into the Cdc28-related protein kinase Ime2 through analysis of replication protein A phosphorylation.
The following RFA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RFA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04340 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183150.1 | |
Accession Version | NM_001183150.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Rfa2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001146). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCAACCT ATCAACCATA TAACGAATAT TCATCAGTAA CGGGCGGTGG CTTTGAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014087.1 |
CDS | 1..822 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183150.1 |
1 | ATGGCAACCT ATCAACCATA TAACGAATAT TCATCAGTAA CGGGCGGTGG CTTTGAGAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications. |
Life with 6000 genes. |