Gene Symbol | YKU70 |
Entrez Gene ID | 855328 |
Full Name | ATP-dependent DNA helicase YKU70 |
Synonyms | HDF1,NES24 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » YKU70 cDNA ORF clone
Gene Symbol | YKU70 |
Entrez Gene ID | 855328 |
Full Name | ATP-dependent DNA helicase YKU70 |
Synonyms | HDF1,NES24 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182791.1 | NP_014011.1 | ATP-dependent DNA helicase YKU70 |
XRCC6 | XP_001105684.1 | |
Gallus gallus (chicken) | XRCC6 | NP_990258.1 |
Danio rerio (zebrafish) | LOC100536337 | XP_003199637.1 |
Canis lupus familiaris (dog) | XRCC6 | XP_005625882.1 |
Mus musculus (house mouse) | Xrcc6 | NP_034377.2 |
Neurospora crassa | NCU08290 | XP_962503.2 |
Xenopus tropicalis (tropical clawed frog) | xrcc6 | NP_001005700.1 |
Danio rerio (zebrafish) | xrcc6 | NP_956198.1 |
Arabidopsis thaliana (thale cress) | KU70 | NP_564012.1 |
Bos taurus (cattle) | XRCC6 | NP_001179175.1 |
Rattus norvegicus (Norway rat) | Xrcc6 | NP_620780.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002690 | XP_312232.5 |
Kluyveromyces lactis | KLLA0C06226g | XP_452475.1 |
Schizosaccharomyces pombe (fission yeast) | pku70 | NP_588445.1 |
Oryza sativa (rice) | Os07g0184900 | NP_001059061.1 |
Homo sapiens (human) | XRCC6 | NP_001460.1 |
Pan troglodytes (chimpanzee) | XRCC6 | XP_521301.3 |
Drosophila melanogaster (fruit fly) | Irbp | NP_536773.1 |
Caenorhabditis elegans (roundworm) | cku-70 | NP_499438.2 |
Saccharomyces cerevisiae (baker's yeast) | YKU70 | NP_014011.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01512 | XP_003714485.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Repair of UV-induced DNA lesions in Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction.
Title: Repair of UV-induced DNA lesions in natural Saccharomyces cerevisiae telomeres is moderated by Sir2 and Sir3, and inhibited by yKu-Sir4 interaction.
the yKu-distal portion of telomeres is bound by Rap1, which in turn reduces the potential for yKu(Yku80 and Yku70 )to mediate NHEJ. These results thus propose a solution to a long-standing conundrum, namely how to accommodate the apparently conflicting functions of Ku on telomeres.
Title: Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome Ends.
We found that the yku70-R456E mutant strain, which has markedly reduced association of Ku at telomeres, maintained WT levels of TLC1 nuclear localization.
Title: The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres.
Yku70 sumoylation upon DNA association strengthens Ku-DNA interaction to promote multiple functions of Ku
Title: Regulation of Ku-DNA association by Yku70 C-terminal tail and SUMO modification.
The TORC1 signal is transduced by the Gln3/Gat1/Ure2 pathway, which controls the levels of the Ku heterodimer, a telomere regulator.
Title: Tor complex 1 controls telomere length by affecting the level of Ku.
The following YKU70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YKU70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04277 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182791.1 | |
Accession Version | NM_001182791.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1809bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | ATP-dependent DNA helicase YKU70 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCGCTCAG TCACTAATGC ATTTGGCAAT AGTGGAGAAC TTAACGATCA AGTGGATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014011.1 |
CDS | 1..1809 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182791.1 |
1 | ATGCGCTCAG TCACTAATGC ATTTGGCAAT AGTGGAGAAC TTAACGATCA AGTGGATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |