Gene Symbol | MRE11 |
Entrez Gene ID | 855264 |
Full Name | MRX complex nuclease subunit |
Synonyms | NGS1,RAD58,XRS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MRE11 cDNA ORF clone
Gene Symbol | MRE11 |
Entrez Gene ID | 855264 |
Full Name | MRX complex nuclease subunit |
Synonyms | NGS1,RAD58,XRS4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001182731.1 | NP_013951.1 | MRX complex nuclease subunit |
Canis lupus familiaris (dog) | MRE11A | XP_005633410.1 |
Danio rerio (zebrafish) | mre11a | NP_001001407.1 |
Schizosaccharomyces pombe (fission yeast) | rad32 | NP_592935.1 |
Neurospora crassa | NCU08730 | XP_963591.2 |
Oryza sativa (rice) | Os04g0635900 | NP_001054012.1 |
Xenopus tropicalis (tropical clawed frog) | mre11a | NP_001107519.1 |
MRE11A | XP_002799798.1 | |
Gallus gallus (chicken) | MRE11A | NP_990109.1 |
Rattus norvegicus (Norway rat) | Mre11a | NP_071615.1 |
Saccharomyces cerevisiae (baker's yeast) | MRE11 | NP_013951.1 |
Kluyveromyces lactis | KLLA0C06930g | XP_452507.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_09555 | XP_003712186.1 |
Pan troglodytes (chimpanzee) | MRE11A | XP_001142422.3 |
Bos taurus (cattle) | GPR83 | NP_001179534.1 |
Mus musculus (house mouse) | Mre11a | NP_061206.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006797 | XP_308950.4 |
Caenorhabditis elegans (roundworm) | mre-11 | NP_505736.2 |
Homo sapiens (human) | MRE11A | NP_005582.1 |
Drosophila melanogaster (fruit fly) | mre11 | NP_523547.1 |
Eremothecium gossypii | AGOS_AFR553C | NP_986100.1 |
Arabidopsis thaliana (thale cress) | MRE11 | NP_200237.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Bowman S, Churcher C, Badcock K, Brown D, Chillingworth T, Connor R, Dedman K, Devlin K, Gentles S, Hamlin N, Hunt S, Jagels K, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Skelton J, Walsh S, Whitehead S, Barrell B
Nature387(6632 Suppl)90-3(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Resection of DNA breaks is impaired when either Sae2 activity is blocked, suggesting roles for both Mre11 and Sae2 nuclease activities in promoting the processing of DNA ends in vivo.
Title: Genetic Separation of Sae2 Nuclease Activity from Mre11 Nuclease Functions in Budding Yeast.
our data suggest a direct role for Sae2 nuclease activity in processing of the DNA structures that arise during replication and DNA damage and provide insights into the mechanism underlying Mre11-Sae2-mediated abrogation of replication stressrelated defects in S. cerevisiae.
Title: Genetic and biochemical evidences reveal novel insights into the mechanism underlying
Xrs2 dependent and independent functions of the Mre11-Rad50 complex orchestrating the cellular response to double-strand DNA breaks have been described.
Title: Xrs2 Dependent and Independent Functions of the Mre11-Rad50 Complex.
The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.
Title: The Saccharomyces cerevisiae Mre11-Rad50-Xrs2 complex promotes trinucleotide repeat expansions independently of homologous recombination.
Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.
Title: S. cerevisiae Mre11 recruits conjugated SUMO moieties to facilitate the assembly and function of the Mre11-Rad50-Xrs2 complex.
The following MRE11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MRE11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi04219 | |
Clone ID Related Accession (Same CDS sequence) | NM_001182731.1 | |
Accession Version | NM_001182731.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | MRX complex nuclease subunit | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001145). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGACTATC CTGATCCAGA CACAATAAGG ATTTTAATTA CTACAGATAA TCATGTGGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_013951.1 |
CDS | 1..2079 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001182731.1 |
1 | ATGGACTATC CTGATCCAGA CACAATAAGG ATTTTAATTA CTACAGATAA TCATGTGGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII. |
Life with 6000 genes. |