Gene Symbol | MGA2 |
Entrez Gene ID | 854851 |
Full Name | Mga2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MGA2 cDNA ORF clone
Gene Symbol | MGA2 |
Entrez Gene ID | 854851 |
Full Name | Mga2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179555.1 | NP_012299.1 | Mga2p |
Saccharomyces cerevisiae (baker's yeast) | MGA2 | NP_012299.1 |
Eremothecium gossypii | AGOS_ACR165W | NP_983567.1 |
Kluyveromyces lactis | KLLA0E17953g | XP_454760.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.
Churcher C, Bowman S, Badcock K, Bankier A, Brown D, Chillingworth T, Connor R, Devlin K, Gentles S, Hamlin N, Harris D, Horsnell T, Hunt S, Jagels K, Jones M, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Rowley N, Skelton J, Smith V, Barrell B
Nature387(6632 Suppl)84-7(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Lipid environment controls the proteolytic activation of Mga2 by stabilizing alternative rotational orientations of the TMH region. Mga2 can act as a lipid-packing sensor in the ER membrane to control the production of unsaturated fatty acids.
Title: A Eukaryotic Sensor for Membrane Lipid Saturation.
the spt23Delta mutant strain shows similar ERG1 expression to wild-type cells, while the mga2Delta/spt23Delta strain shows reduced ERG1 expression, comparable to the mga2Delta, suggesting that the role of regulation of ERG1 transcription is unique to Mga2p.
Title: A role for MGA2, but not SPT23, in activation of transcription of ERG1 in Saccharomyces cerevisiae.
identified, using mass spectrometry analysis of in vitro ubiquitinated Mga2p120-Mga2p90 complex, that lysine residues 983 and 985 contained within the carboxy-terminal domain of Mga2p120 are Rsp5p-directed Ub-conjugation sites
Title: Identification of lysines within membrane-anchored Mga2p120 that are targets of Rsp5p ubiquitination and mediate mobilization of tethered Mga2p90.
Rsp5p, Spt23p and Mga2p may participate in the control of the homeostasis of lipids and lipid particles.
Title: Rsp5p ubiquitin ligase and the transcriptional activators Spt23p and Mga2p are involved in co-regulation of biosynthesis of end products of the mevalonate pathway and triacylglycerol in yeast Saccharomyces cerevisiae.
WW domains 2 and 3 of Rsp5p play overlapping roles in binding to the WW domain-binding site site on Spt23p and Mga2p
Title: WW domains 2 and 3 of Rsp5p play overlapping roles in binding to the LPKY motif of Spt23p and Mga2p.
The following MGA2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MGA2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03863 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179555.1 | |
Accession Version | NM_001179555.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3342bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Mga2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001141). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCAGCAGA ACAGTGAGTT CTTAACGGAA ACACCTGGAA GCGACCCTCA TATATCTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012299.1 |
CDS | 1..3342 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179555.1 |
1 | ATGCAGCAGA ACAGTGAGTT CTTAACGGAA ACACCTGGAA GCGACCCTCA TATATCTCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IX. |
Life with 6000 genes. |