Gene Symbol | IRR1 |
Entrez Gene ID | 854786 |
Full Name | Irr1p |
Synonyms | SCC3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » IRR1 cDNA ORF clone
Gene Symbol | IRR1 |
Entrez Gene ID | 854786 |
Full Name | Irr1p |
Synonyms | SCC3 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179376.1 | NP_012238.1 | Irr1p |
Saccharomyces cerevisiae (baker's yeast) | IRR1 | NP_012238.1 |
Kluyveromyces lactis | KLLA0F27797g | XP_456316.1 |
Eremothecium gossypii | AGOS_ADL093W | NP_984003.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.
Churcher C, Bowman S, Badcock K, Bankier A, Brown D, Chillingworth T, Connor R, Devlin K, Gentles S, Hamlin N, Harris D, Horsnell T, Hunt S, Jagels K, Jones M, Lye G, Moule S, Odell C, Pearson D, Rajandream M, Rice P, Rowley N, Skelton J, Smith V, Barrell B
Nature387(6632 Suppl)84-7(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We show that residues Y371 and K372 within the SCD are critical for viability and chromosome condensation but dispensable for cohesion. However, scc3 Y371A and scc3 K372A bind normally to Mcd1
Title: A conserved domain in the scc3 subunit of cohesin mediates the interaction with both mcd1 and the cohesin loader complex.
Scc3 C-terminal domain binds Scc1 and promotes de-acetylation of Smc3 upon Scc1 cleavage.
Title: Structure and function of cohesin's Scc3/SA regulatory subunit.
expression of 33 genes is affected by the presence of the mutated Irr1-1p and identify those genes. This supports the suggested role of Irr1p in the regulation of transcription. Irr1p may interact with elements of transcriptional coactivator Mediator
Title: Cohesin Irr1/Scc3 is likely to influence transcription in Saccharomyces cerevisiae via interaction with Mediator complex.
The expression of MCD1 was not subject to Scc3 regulation in vegetative cells. Scc3 and Smc1 are both required for the production of the meiosis-specific subunit Rec8.
Title: Cohesin plays a dual role in gene regulation and sister-chromatid cohesion during meiosis in Saccharomyces cerevisiae.
The F658G substitutionin Irr1 was found to induce marked changes in the general shape of the predicted protein which retains its ability to interact with Scc1p, another component of the cohesin complex.
Title: The F658G substitution in Saccharomyces cerevisiae cohesin Irr1/Scc3 is semi-dominant in the diploid and disturbs mitosis, meiosis and the cell cycle.
The following IRR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IRR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03807 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179376.1 | |
Accession Version | NM_001179376.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3453bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Irr1p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001141). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACTGCTG TGCGTCGCTC AACTAGAATA AGGACTAAAT CTCAAGTTAT TGAGGAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012238.1 |
CDS | 1..3453 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179376.1 |
1 | ATGACTGCTG TGCGTCGCTC AACTAGAATA AGGACTAAAT CTCAAGTTAT TGAGGAAGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IX. |
Life with 6000 genes. |