Gene Symbol | LAS17 |
Entrez Gene ID | 854353 |
Full Name | actin-binding protein LAS17 |
Synonyms | BEE1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » LAS17 cDNA ORF clone
Gene Symbol | LAS17 |
Entrez Gene ID | 854353 |
Full Name | actin-binding protein LAS17 |
Synonyms | BEE1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183600.1 | NP_014824.1 | actin-binding protein LAS17 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Studies indicate that the WASP homologue Las17 is able to nucleate actin independently of Arp2/3 through the function of G-actin-binding activities in its polyproline region.
Title: WASP family proteins, more than Arp2/3 activators.
LGM has relatively lower potency compared to the previously known Las17 G-actin-binding motif, WH2.
Title: A second Las17 monomeric actin-binding motif functions in Arp2/3-dependent actin polymerization during endocytosis.
A model is proposed in which actin filaments bind Vps1 during invagination, and this interaction is important to transduce the force of actin polymerization to the membrane to drive successful scission.
Title: A dynamin-actin interaction is required for vesicle scission during endocytosis in yeast.
polyproline domain able to nucleate actin filaments independently of Arp2/3
Title: A novel actin-binding motif in Las17/WASP nucleates actin filaments independently of Arp2/3.
Lsb1 and/or Lsb2 full-length proteins inhibit Las17-mediated actin polymerization
Title: Lsb1 is a negative regulator of las17 dependent actin polymerization involved in endocytosis.
The following LAS17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAS17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03480 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183600.1 | |
Accession Version | NM_001183600.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | actin-binding protein LAS17 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGACTCC TAAACTCTTC AGATAAGGAA ATTATCAAAA GGGCTCTACC AAAAGCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014824.1 |
CDS | 1..1902 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183600.1 |
1 | ATGGGACTCC TAAACTCTTC AGATAAGGAA ATTATCAAAA GGGCTCTACC AAAAGCGTCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |