Gene Symbol | NFI1 |
Entrez Gene ID | 854327 |
Full Name | SUMO ligase NFI1 |
Synonyms | SIZ2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » NFI1 cDNA ORF clone
Gene Symbol | NFI1 |
Entrez Gene ID | 854327 |
Full Name | SUMO ligase NFI1 |
Synonyms | SIZ2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183575.1 | NP_014799.1 | SUMO ligase NFI1 |
Kluyveromyces lactis | KLLA0A02189g | XP_451097.1 |
Danio rerio (zebrafish) | pias4b | NP_956637.2 |
Saccharomyces cerevisiae (baker's yeast) | NFI1 | NP_014799.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
double-strand break relocation to the nuclear envelope depends on SUMOylation mediated by the E3 ligases Siz2 and Mms21
Title: PolySUMOylation by Siz2 and Mms21 triggers relocation of DNA breaks to nuclear pores through the Slx5/Slx8 STUbL.
DNA break induction, the budding yeast SUMO ligase Siz2 collaborates with the ssDNA-binding complex RPA (replication protein A) to induce the sumoylation of recombination factors and confer damage resistance
Title: DNA break-induced sumoylation is enabled by collaboration between a SUMO ligase and the ssDNA-binding complex RPA.
The sumoylating activity of Siz2 at the nuclear periphery acts to maintain a balance of sumoylation that supports the localization of Sir2/Sir4 to these silent regions.
Title: The SUMO E3 ligase Siz2 exerts a locus-dependent effect on gene silencing in Saccharomyces cerevisiae.
The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.
Title: The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast.
data suggest that SUMO attachment negatively regulates Flp1 levels, which may partially account for the increased 2 microm copy number in the siz1Delta siz2Delta strain
Title: Misregulation of 2 microm circle copy number in a SUMO pathway mutant.
The following NFI1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NFI1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03457 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183575.1 | |
Accession Version | NM_001183575.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2181bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | SUMO ligase NFI1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCAAGTG TCATGTCAAA TAATAATAAT AATAATAATA ATAATAATGC CAGTTATATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014799.1 |
CDS | 1..2181 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183575.1 |
1 | ATGGCAAGTG TCATGTCAAA TAATAATAAT AATAATAATA ATAATAATGC CAGTTATATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |