Gene Symbol | SGT2 |
Entrez Gene ID | 854168 |
Full Name | Sgt2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SGT2 cDNA ORF clone
Gene Symbol | SGT2 |
Entrez Gene ID | 854168 |
Full Name | Sgt2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001183426.1 | NP_014649.1 | Sgt2p |
Eremothecium gossypii | AGOS_ACR005W | NP_983408.1 |
Bos taurus (cattle) | SGTB | NP_001179720.1 |
Mus musculus (house mouse) | Sgtb | NP_659087.1 |
Saccharomyces cerevisiae (baker's yeast) | SGT2 | NP_014649.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC1142.02c | XP_001713087.1 |
Homo sapiens (human) | SGTB | NP_061945.1 |
Gallus gallus (chicken) | SGTB | NP_001026589.1 |
Danio rerio (zebrafish) | sgta | NP_001002225.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003052 | XP_311818.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_05438 | XP_003710298.1 |
Rattus norvegicus (Norway rat) | Sgtb | NP_853660.1 |
Neurospora crassa | NCU10273 | XP_001728325.1 |
Xenopus tropicalis (tropical clawed frog) | sgtb | XP_002934237.2 |
Pan troglodytes (chimpanzee) | SGTB | XP_526906.2 |
Canis lupus familiaris (dog) | SGTB | XP_535258.1 |
Drosophila melanogaster (fruit fly) | Sgt | NP_001246058.1 |
Kluyveromyces lactis | KLLA0D01155g | XP_453122.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
Dujon B, Albermann K, Aldea M, Alexandraki D, Ansorge W, Arino J, Benes V, Bohn C, Bolotin-Fukuhara M, Bordonn? R, Boyer J, Camasses A, Casamayor A, Casas C, Ch?ret G, Cziepluch C, Daignan-Fornier B, Dang DV, de Haan M, Delius H, Durand P, Fairhead C, Feldmann H, Gaillon L, Kleine K
Nature387(6632 Suppl)98-102(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Report demonstrated that Ybr137wp and the Sgt2 TPR domain interact directly.
Title: Structural and functional characterization of ybr137wp implicates its involvement in the targeting of tail-anchored proteins to membranes.
SGTA(Sgt2) associates with and specifically regulates the androgen, glucocorticoid, and progesterone receptors and has no effect on the mineralocorticoid and estrogen receptors in both yeast and mammalian cell-based reporter assays.
Title: The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors.
The crystal structure of Sgt2 dimerization domain complexed with the Get5 Ubl domain (Sgt2N-Get5Ubl) is reported.
Title: Structure of the Sgt2 dimerization domain complexed with the Get5 UBL domain involved in the targeting of tail-anchored membrane proteins to the endoplasmic reticulum.
solve a structure of the Sgt2_NT/Get5_UBL complex, validate it via site-directed mutagenesis, and empirically determine its stoichiometry using relaxation experiments and isothermal titration calorimetry
Title: Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteins.
Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface.
Title: Structures of the Sgt2/SGTA dimerization domain with the Get5/UBL4A UBL domain reveal an interaction that forms a conserved dynamic interface.
The following SGT2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SGT2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi03322 | |
Clone ID Related Accession (Same CDS sequence) | NM_001183426.1 | |
Accession Version | NM_001183426.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Sgt2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001147). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAGCAT CAAAAGAAGA AATTGCTGCC CTTATTGTAA ACTACTTTTC TTCCATTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_014649.1 |
CDS | 1..1041 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001183426.1 |
1 | ATGTCAGCAT CAAAAGAAGA AATTGCTGCC CTTATTGTAA ACTACTTTTC TTCCATTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XV. |
Life with 6000 genes. |