Gene Symbol | RAD27 |
Entrez Gene ID | 853747 |
Full Name | multifunctional nuclease RAD27 |
Synonyms | ERC11,FEN1,RTH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » RAD27 cDNA ORF clone
Gene Symbol | RAD27 |
Entrez Gene ID | 853747 |
Full Name | multifunctional nuclease RAD27 |
Synonyms | ERC11,FEN1,RTH1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179679.1 | NP_012809.1 | multifunctional nuclease RAD27 |
Homo sapiens (human) | FEN1 | NP_004102.1 |
Canis lupus familiaris (dog) | FEN1 | XP_005631709.1 |
Gallus gallus (chicken) | FEN1 | NP_001072959.1 |
Drosophila melanogaster (fruit fly) | Fen1 | NP_523765.1 |
Xenopus tropicalis (tropical clawed frog) | fen1 | NP_001017005.1 |
FEN1 | XP_002799575.1 | |
Bos taurus (cattle) | FEN1 | NP_001030285.1 |
Rattus norvegicus (Norway rat) | Fen1 | NP_445882.1 |
Danio rerio (zebrafish) | fen1 | NP_942115.1 |
Caenorhabditis elegans (roundworm) | crn-1 | NP_491168.1 |
Kluyveromyces lactis | KLLA0F02992g | XP_455215.1 |
Neurospora crassa | NCU10776 | XP_001728355.1 |
Arabidopsis thaliana (thale cress) | AT5G26680 | NP_001154740.1 |
Mus musculus (house mouse) | Fen1 | NP_032025.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011448 | XP_317855.2 |
Saccharomyces cerevisiae (baker's yeast) | RAD27 | NP_012809.1 |
Oryza sativa (rice) | Os05g0540100 | NP_001056179.1 |
Pan troglodytes (chimpanzee) | FEN1 | XP_003951955.1 |
Eremothecium gossypii | AGOS_ABL052C | NP_982895.2 |
Schizosaccharomyces pombe (fission yeast) | rad2 | NP_594972.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_03419 | XP_003716519.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rad2 and rad27 overexpression increases genomic instability in yeast. Rad2 and Rad27 causes DNA breaks that are processed by different repair functions.
Title: Differential effect of the overexpression of Rad2/XPG family endonucleases on genome integrity in yeast and human cells.
our findings underscore the importance of Rad27p in the maintenance of mtDNA, and demonstrate that it participates in multiple DNA repair pathways in mitochondria, unlinked to nuclear phenotypes.
Title: Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in
Data show that wild-type Rad27 proteins are more stably associated with chromatin than tailless Rad27.
Title: Physical and functional interactions between nucleosomes and Rad27, a critical component of DNA processing during DNA metabolism.
findings indicate that the N-terminal region of Mus81 acts as a landing pad to interact with Rad27 and that Mus81 and Rad27 work conjointly for efficient removal of various aberrant DNA structures
Title: A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repair.
C-terminal 16-amino acid fragment of Rad27 was sufficient and necessary for the stimulation of both Rad27 and Dna2.
Title: The trans-autostimulatory activity of Rad27 suppresses dna2 defects in Okazaki fragment processing.
The following RAD27 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAD27 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02951 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179679.1 | |
Accession Version | NM_001179679.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1149bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | multifunctional nuclease RAD27 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGTATTA AAGGTTTGAA TGCAATTATA TCGGAACATG TTCCCTCTGC TATCAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012809.1 |
CDS | 1..1149 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179679.1 |
1 | ATGGGTATTA AAGGTTTGAA TGCAATTATA TCGGAACATG TTCCCTCTGC TATCAGGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |