Gene Symbol | SAC1 |
Entrez Gene ID | 853668 |
Full Name | phosphatidylinositol-3-phosphatase SAC1 |
Synonyms | RSD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SAC1 cDNA ORF clone
Gene Symbol | SAC1 |
Entrez Gene ID | 853668 |
Full Name | phosphatidylinositol-3-phosphatase SAC1 |
Synonyms | RSD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001179777.1 | NP_012710.1 | phosphatidylinositol-3-phosphatase SAC1 |
Bos taurus (cattle) | SACM1L | NP_001095601.1 |
Mus musculus (house mouse) | Sacm1l | NP_109617.1 |
Drosophila melanogaster (fruit fly) | Sac1 | NP_001189016.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_11279 | XP_003714069.1 |
Arabidopsis thaliana (thale cress) | RHD4 | NP_190714.2 |
Pan troglodytes (chimpanzee) | SACM1L | XP_516409.4 |
Caenorhabditis elegans (roundworm) | sac-1 | NP_492518.1 |
Eremothecium gossypii | AGOS_AER447C | NP_985302.1 |
Gallus gallus (chicken) | SACM1L | XP_418799.4 |
Canis lupus familiaris (dog) | SACM1L | XP_541911.2 |
Danio rerio (zebrafish) | sacm1la | NP_001038343.1 |
Danio rerio (zebrafish) | sacm1lb | NP_001074093.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000891 | XP_316868.5 |
Schizosaccharomyces pombe (fission yeast) | SPBC19F5.03 | NP_596541.1 |
Arabidopsis thaliana (thale cress) | ATSAC1B | NP_201403.2 |
Homo sapiens (human) | SACM1L | NP_054735.3 |
SACM1L | XP_001114514.1 | |
Rattus norvegicus (Norway rat) | Sacm1l | NP_446250.1 |
Saccharomyces cerevisiae (baker's yeast) | SAC1 | NP_012710.1 |
Kluyveromyces lactis | KLLA0B14388g | XP_452171.1 |
Neurospora crassa | NCU00896 | XP_964812.1 |
Oryza sativa (rice) | Os02g0554300 | NP_001047117.1 |
Oryza sativa (rice) | Os11g0309000 | NP_001067755.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome XI.
Dujon B, Alexandraki D, Andr? B, Ansorge W, Baladron V, Ballesta JP, Banrevi A, Bolle PA, Bolotin-Fukuhara M, Bossier P, Bou G, Boyer J, Bultrago MJ, Cheret G, Colleaux L, Dalgnan-Fornler B, del Rey F, Dlon C, Domdey H, D?sterhoft A, D?sterhus S, Entlan KD, Erfle H, Esteban PF, Feldmann H, Fernandes L, Robo GM, Fritz C, Fukuhara H, Gabel C, Gaillon L, Carcia-Cantalejo JM, Garcia-Ramirez JJ, Gent NE, Ghazvini M, Goffeau A, Gonzal?z A, Grothues D, Guerreiro P, Hegemann J, Hewitt N, Hilger F, Hollenberg CP, Horaitis O, Indge KJ, Jacquier A, James CM, Jauniaux C, Jimenez A, Keuchel H, Kirchrath L, Kleine K, K?tter P, Legrain P, Liebl S, Louis EJ, Maia e Silva A, Marck C, Monnier AL, M?stl D, M?ller S, Obermaier B, Oliver SG, Pallier C, Pascolo S, Pfeiffer F, Philippsen P, Planta RJ, Pohl FM, Pohl TM, P?hlmann R, Portetelle D, Purnelle B, Puzos V, Ramezani Rad M, Rasmussen SW, Remacha M, Revuelta JL, Richard GF, Rieger M, Rodrigues-Pousada C, Rose M, Rupp T, Santos MA, Schwager C, Sensen C, Skala J, Soares H, Sor F, Stegemann J, Tettelin H, Thierry A, Tzermia M, Urrestarazu LA, van Dyck L, Van Vliet-Reedijk JC, Valens M, Vandenbo M, Vilela C, Vissers S, von Wettstein D, Voss H, Wiemann S, Xu G, Zimmermann J, Haasemann M, Becker I, Mewes HW
Nature369(6479)371-8(1994 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
this study showed that the PI4P-phosphatase Sac1p, by maintaining a PI4P gradient at the endoplasmic reticulum / plasma membrane interface, drove phosphatidylserine transport.
Title: INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate.
Disruption of the Sac1-Vps74 interface results in a broader distribution of phosphatidylinositol 4-phosphate within the Golgi apparatus and failure to maintain residence of a medial Golgi mannosyltransferase.
Title: Sac1-Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus.
Collectively, these results suggested that Sac1 is involved in the maintenance of a normal rate of biosynthesis and distribution of phosphatidylserine.
Title: Involvement of Sac1 phosphoinositide phosphatase in the metabolism of phosphatidylserine in the yeast Saccharomyces cerevisiae.
Sac1 trafficking depends on Hog1 function.
Title: Metabolic activation of the HOG MAP kinase pathway by Snf1/AMPK regulates lipid signaling at the Golgi.
Vps74 binds directly to the catalytic domain of Sac1
Title: Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase.
The following SAC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SAC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02888 | |
Clone ID Related Accession (Same CDS sequence) | NM_001179777.1 | |
Accession Version | NM_001179777.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1872bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | phosphatidylinositol-3-phosphatase SAC1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001143). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGACAGGTC CAATAGTGTA CGTTCAAAAT GCGGACGGTA TCTTCTTCAA GCTTGCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012710.1 |
CDS | 1..1872 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001179777.1 |
1 | ATGACAGGTC CAATAGTGTA CGTTCAAAAT GCGGACGGTA TCTTCTTCAA GCTTGCTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome XI. |