Gene Symbol | PBS2 |
Entrez Gene ID | 853313 |
Full Name | mitogen-activated protein kinase kinase PBS2 |
Synonyms | HOG4,SFS4,SSK4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » PBS2 cDNA ORF clone
Gene Symbol | PBS2 |
Entrez Gene ID | 853313 |
Full Name | mitogen-activated protein kinase kinase PBS2 |
Synonyms | HOG4,SFS4,SSK4 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181561.2 | NP_012407.2 | mitogen-activated protein kinase kinase PBS2 |
Saccharomyces cerevisiae (baker's yeast) | PBS2 | NP_012407.2 |
Kluyveromyces lactis | KLLA0E15313g | XP_454640.1 |
Eremothecium gossypii | AGOS_AFL217C | NP_985333.1 |
Danio rerio (zebrafish) | map2k4b | NP_001082890.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show that that two alternative MAPKKs, Pbs2 and Mkk2, can be forced to functionally replace the mating MAPKK Ste7, but only if the proper set of recruitment interactions are grafted onto their catalytic domains.
Title: Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase.
In the N-terminal noncatalytic region of Pbs2, there is a specific Hog1-binding domain, HBD-1.
Title: Two adjacent docking sites in the yeast Hog1 mitogen-activated protein (MAP) kinase differentially interact with the Pbs2 MAP kinase kinase and the Ptp2 protein tyrosine phosphatase.
hypersensitivity to salt and other stress conditions was due to the deletion of 5 base pairs close to position 936 bp in the PBS2 gene essential for HOG signal pathway regulation under salt stress
Title: [Identification of the gene correlated with salt stress in the Saccharomyces cerevisiae 263-H9 mutant].
Here we show that by replacing C-terminal region of Dpbs2p with the homologous region of Pbs2p we could abrogate partial complementation exhibited by Dpbs2p and this was achieved due to increase in nuclear translocation of Hog1p.
Title: Evidence that C-terminal non-kinase domain of Pbs2p has a role in high osmolarity-induced nuclear localization of Hog1p.
The following PBS2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PBS2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02587 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181561.2 | |
Accession Version | NM_001181561.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | mitogen-activated protein kinase kinase PBS2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001142). On Apr 26, 2011 this sequence version replaced NM_001181561.1. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGAAGACA AGTTTGCTAA CCTCAGTCTC CATGAGAAAA CTGGTAAGTC ATCTATCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012407.2 |
CDS | 1..2007 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181561.2 |
1 | ATGGAAGACA AGTTTGCTAA CCTCAGTCTC CATGAGAAAA CTGGTAAGTC ATCTATCCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. |