Gene Symbol | CDC6 |
Entrez Gene ID | 853244 |
Full Name | AAA family ATPase CDC6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC6 cDNA ORF clone
Gene Symbol | CDC6 |
Entrez Gene ID | 853244 |
Full Name | AAA family ATPase CDC6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181627.1 | NP_012341.1 | AAA family ATPase CDC6 |
Saccharomyces cerevisiae (baker's yeast) | CDC6 | NP_012341.1 |
Neurospora crassa | NCU02776 | XP_964271.1 |
Eremothecium gossypii | AGOS_AFR621C | NP_986168.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_01614 | XP_003714598.1 |
Kluyveromyces lactis | KLLA0C03586g | XP_452356.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
Galibert F, Alexandraki D, Baur A, Boles E, Chalwatzis N, Chuat JC, Coster F, Cziepluch C, De Haan M, Domdey H, Durand P, Entian KD, Gatius M, Goffeau A, Grivell LA, Hennemann A, Herbert CJ, Heumann K, Hilger F, Hollenberg CP, Huang ME, Jacq C, Jauniaux JC, Katsoulou C, Karpfinger-Hartl L
The EMBO journal15(9)2031-49(1996 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Cdc6 ATP hydrolysis is therefore required for Cdc6 disengagement from the pre-replicative complex after helicase loading to advance subsequent steps in helicase activation in vivo.
Title: Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.
Cdc6 degradation triggered by Mck1 kinase was enhanced upon DNA damage.
Title: Cdc6 degradation requires phosphodegron created by GSK-3 and Cdk1 for SCFCdc4 recognition in Saccharomyces cerevisiae.
Data indicate that Cdt1-MCM2-7 complex activates ORC/Cdc6 ATP-hydrolysis to promote helicase loading.
Title: An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
Tom1 and the Dia2 control Cdc6 degradation in G1 phase.
Title: The Hect domain E3 ligase Tom1 and the F-box protein Dia2 control Cdc6 degradation in G1 phase.
We propose that both CDK and Mck1 kinases are required for Cdc6 degradation to ensure a tight control of DNA replication.
Title: A yeast GSK-3 kinase Mck1 promotes Cdc6 degradation to inhibit DNA re-replication.
The following CDC6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02529 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181627.1 | |
Accession Version | NM_001181627.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1542bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | AAA family ATPase CDC6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001142). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCAGCTA TACCAATAAC TCCAACTAAG CGTATCAGAA GAAATCTATT TGACGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_012341.1 |
CDS | 1..1542 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181627.1 |
1 | ATGTCAGCTA TACCAATAAC TCCAACTAAG CGTATCAGAA GAAATCTATT TGACGATGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. |