Gene Symbol | MSB2 |
Entrez Gene ID | 852897 |
Full Name | Msb2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MSB2 cDNA ORF clone
Gene Symbol | MSB2 |
Entrez Gene ID | 852897 |
Full Name | Msb2p |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001181143.3 | NP_011528.3 | Msb2p |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The extracellular cysteine-rich domain of the transmembrane-anchor protein Opy2 binds to the Hkr1-Msb2 homology domain of the putative osmosensor Msb2 and the formation of the Opy2-Msb2 complex is essential for osmotic activation of Hog1.
Title: Binding of the Extracellular Eight-Cysteine Motif of Opy2 to the Putative Osmosensor Msb2 Is Essential for Activation of the Yeast High-Osmolarity Glycerol Pathway.
Our results confirm the existence of negative feedback systems targeting the protein levels of Ste11 and Msb2 and also hint at changes in the dissociation rates of intermediate signaling complexes
Title: Msb2 is a Ste11 membrane concentrator required for full activation of the HOG pathway.
interaction between Ste20 and Sho1 contributed to the activation of Hog1 by Hkr1, but not by Msb2.
Title: Yeast osmosensors Hkr1 and Msb2 activate the Hog1 MAPK cascade by different mechanisms.
The osmosensor Hkr1 is required for activation of the yeast cell wall integrity MAPK pathway signaling but Msb2 is not.
Title: Activation of the yeast cell wall integrity MAPK pathway by zymolyase depends on protease and glucanase activities and requires the mucin-like protein Hkr1 but not Msb2.
Data showed that Msb2p had a function in cell polarization through the adaptor protein Sho1p that Hkr1p did not.
Title: The signaling mucins Msb2 and Hkr1 differentially regulate the filamentation mitogen-activated protein kinase pathway and contribute to a multimodal response.
The following MSB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02246 | |
Clone ID Related Accession (Same CDS sequence) | NM_001181143.3 | |
Accession Version | NM_001181143.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3921bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | Msb2p | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001181143.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGCAGTTTC CATTCGCTTG TCTCCTATCG ACCCTTGTAA TTAGTGGGTC ATTGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011528.3 |
CDS | 1..3921 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001181143.3 |
1 | ATGCAGTTTC CATTCGCTTG TCTCCTATCG ACCCTTGTAA TTAGTGGGTC ATTGGCCCGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |