Gene Symbol | MAD1 |
Entrez Gene ID | 852794 |
Full Name | coiled-coil domain-containing protein MAD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MAD1 cDNA ORF clone
Gene Symbol | MAD1 |
Entrez Gene ID | 852794 |
Full Name | coiled-coil domain-containing protein MAD1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180951.3 | NP_011429.3 | coiled-coil domain-containing protein MAD1 |
Saccharomyces cerevisiae (baker's yeast) | MAD1 | NP_011429.3 |
Kluyveromyces lactis | KLLA0E19141g | XP_454817.1 |
Schizosaccharomyces pombe (fission yeast) | mad1 | NP_595516.1 |
Neurospora crassa | NCU04428 | XP_957505.2 |
Magnaporthe oryzae (rice blast fungus) | MGG_04908 | XP_003712395.1 |
Eremothecium gossypii | AGOS_AFL065C | NP_985483.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Tettelin H, Agostoni Carbone ML, Albermann K, Albers M, Arroyo J, Backes U, Barreiros T, Bertani I, Bjourson AJ, Br?ckner M, Bruschi CV, Carignani G, Castagnoli L, Cerdan E, Clemente ML, Coblenz A, Coglievina M, Coissac E, Defoor E, Del Bino S, Delius H, Delneri D, de Wergifosse P, Dujon B, Kleine K
Nature387(6632 Suppl)81-4(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mad1 recruitment to the kinetochore and it's role in the spindle assembly checkpoint
Title: Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions.
Mad1 is recruited by detached kinetochores competing with alternate other sites in nucleus: Mad1 pool is small enough to be fully depleted by one pair of detached kinetochores. Lateral attachment licenses Mad1 removal from kinetochores after kinetic delay
Title: Control of the spindle checkpoint by lateral kinetochore attachment and limited Mad1 recruitment.
Mad1p senses unattached kinetochores and, by altering nuclear pore complex transport activity, regulates the nuclear environment of the spindle.
Title: Mitosis-specific regulation of nuclear transport by the spindle assembly checkpoint protein Mad1p.
cells need the normal Mad2:Mad1 ratio to respond to chromosomes that are not under tension.
Title: Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis.
Only the C terminus is required for spindle assembly checkpoint (SAC) function and the nuclear pore complex, through Nup53p, may act to regulate the duration of the SAC response.
Title: Interactions between Mad1p and the nuclear transport machinery in the yeast Saccharomyces cerevisiae.
The following MAD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi02158 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180951.3 | |
Accession Version | NM_001180951.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2250bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | coiled-coil domain-containing protein MAD1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001139). On Jul 30, 2012 this sequence version replaced NM_001180951.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATGTGA GAGCGGCATT GCAATGTTTC TTCAGTGCAT TGAGTGGACG ATTCACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_011429.3 |
CDS | 1..2250 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180951.3 |
1 | ATGGATGTGA GAGCGGCATT GCAATGTTTC TTCAGTGCAT TGAGTGGACG ATTCACTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII. |
Life with 6000 genes. |