Gene Symbol | CNS1 |
Entrez Gene ID | 852452 |
Full Name | HSP70/90 family co-chaperone CNS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CNS1 cDNA ORF clone
Gene Symbol | CNS1 |
Entrez Gene ID | 852452 |
Full Name | HSP70/90 family co-chaperone CNS1 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178503.1 | NP_009713.1 | HSP70/90 family co-chaperone CNS1 |
Homo sapiens (human) | TTC4 | NP_004614.3 |
Pan troglodytes (chimpanzee) | TTC4 | XP_001153260.1 |
Mus musculus (house mouse) | Ttc4 | NP_082485.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06164 | XP_003712044.1 |
Drosophila melanogaster (fruit fly) | Dpit47 | NP_001260729.1 |
Eremothecium gossypii | AGOS_AGL268C | NP_986399.1 |
Bos taurus (cattle) | TTC4 | NP_001015554.1 |
Danio rerio (zebrafish) | ttc4 | NP_001002122.1 |
Caenorhabditis elegans (roundworm) | C17G10.2 | NP_495087.1 |
Kluyveromyces lactis | KLLA0B09966g | XP_451972.1 |
Schizosaccharomyces pombe (fission yeast) | cns1 | NP_594238.1 |
Xenopus tropicalis (tropical clawed frog) | ttc4 | XP_002931478.2 |
Canis lupus familiaris (dog) | TTC4 | XP_853176.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012044 | XP_320482.3 |
Saccharomyces cerevisiae (baker's yeast) | CNS1 | NP_009713.1 |
Neurospora crassa | NCU06340 | XP_962374.1 |
TTC4 | XP_001114145.1 | |
Gallus gallus (chicken) | TTC4 | XP_426665.3 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CNS1 binds intact ribosome.
Title: The Hsp90 cochaperones Cpr6, Cpr7, and Cns1 interact with the intact ribosome.
overexpression of other co-chaperones further disrupts the essential functions of Cns1 and Sgt1. However, the specificity of the negative effects indicates that only a subset of co-chaperones competes with Sgt1 or Cns1 for binding to Hsp90.
Title: Mutation of essential Hsp90 co-chaperones SGT1 or CNS1 renders yeast hypersensitive to overexpression of other co-chaperones.
Cns1p, a cochaperone for Hsp70 and Hsp90 chaperones, is a strong inhibitor of TBSV replication.
Title: Identification of novel host factors via conserved domain search: Cns1 cochaperone is a novel restriction factor of tombusvirus replication in yeast.
Cns1 is a potent cochaperone of Ssa1
Title: Cns1 is an activator of the Ssa1 ATPase activity.
The following CNS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CNS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01857 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178503.1 | |
Accession Version | NM_001178503.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1158bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | HSP70/90 family co-chaperone CNS1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGAGCTCCG TTAACGCAAA TGGAGGATAT ACCAAACCAC AAAAATATGT GCCAGGGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009713.1 |
CDS | 1..1158 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178503.1 |
1 | ATGAGCTCCG TTAACGCAAA TGGAGGATAT ACCAAACCAC AAAAATATGT GCCAGGGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |