Gene Symbol | SUP45 |
Entrez Gene ID | 852440 |
Full Name | translation termination factor eRF1 |
Synonyms | SAL4,SUP1,SUP47 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SUP45 cDNA ORF clone
Gene Symbol | SUP45 |
Entrez Gene ID | 852440 |
Full Name | translation termination factor eRF1 |
Synonyms | SAL4,SUP1,SUP47 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178491.3 | NP_009701.3 | translation termination factor eRF1 |
Pan troglodytes (chimpanzee) | ETF1 | XP_001171542.1 |
Canis lupus familiaris (dog) | ETF1 | NP_001239075.1 |
Bos taurus (cattle) | ETF1 | NP_001069722.1 |
Mus musculus (house mouse) | Etf1 | NP_659115.3 |
Caenorhabditis elegans (roundworm) | etf-1 | NP_001024107.2 |
Schizosaccharomyces pombe (fission yeast) | sup45 | NP_594680.1 |
Homo sapiens (human) | ETF1 | NP_004721.1 |
ETF1 | XP_001112899.2 | |
Arabidopsis thaliana (thale cress) | ERF1-1 | NP_199599.1 |
Xenopus tropicalis (tropical clawed frog) | etf1 | NP_989035.1 |
Gallus gallus (chicken) | ETF1 | XP_414511.2 |
Danio rerio (zebrafish) | etf1 | NP_958868.1 |
Drosophila melanogaster (fruit fly) | eRF1 | NP_649210.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_06266 | XP_003717326.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010310 | XP_319502.1 |
Saccharomyces cerevisiae (baker's yeast) | SUP45 | NP_009701.3 |
Eremothecium gossypii | AGOS_AER028C | NP_984888.1 |
Rattus norvegicus (Norway rat) | Etf1 | NP_001008345.1 |
Kluyveromyces lactis | KLLA0C11231g | XP_452701.1 |
Neurospora crassa | NCU00410 | XP_957296.1 |
Oryza sativa (rice) | Os01g0939500 | NP_001045349.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We demonstrated that interaction of [SWI+] and [PIN+] causes inactivation of SUP45 gene that leads to nonsense suppression. Our data show that prion interactions may cause heritable traits in Saccharomyces cerevisiae.
Title: Interaction of Prions Causes Heritable Traits in Saccharomyces cerevisiae.
In this work, the authors show that nonsense and missense mutations in the SUP45, but not the SUP35, gene abolish diploid pseudohyphal and haploid invasive growth.
Title: The translation termination factor eRF1 (Sup45p) of Saccharomyces cerevisiae is required for pseudohyphal growth and invasion.
Analysis of the L123 systematic mutants of eRF1 suggested that this amino acid functions in stop codon discrimination in a manner coupled with eRF3 binding, and distinctive from previously reported adjacent residues.
Title: Genetic analysis of L123 of the tRNA-mimicking eukaryote release factor eRF1, an amino acid residue critical for discrimination of stop codons.
We characterized a region of the eRF1 N-terminal domain, the P1 pocket, that we had previously shown to be involved in termination efficiency. We identified two residues, arginine 65 and lysine 109, as critical for recognition of the three stop codons.
Title: New insights into stop codon recognition by eRF1.
Prion-like determinant [NSI+] decreases the relative amounts of SUP45 mRNA that causes a decrease in the amounts of Sup45 protein.
Title: [Prion-like determinant [NSI+] decreases expression of the SUP45 gene in Saccharomyces cerevisiae].
The following SUP45 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SUP45 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01846 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178491.3 | |
Accession Version | NM_001178491.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1314bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | translation termination factor eRF1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). On Jul 30, 2012 this sequence version replaced NM_001178491.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGATAACG AGGTTGAAAA AAATATTGAG ATCTGGAAGG TCAAGAAGTT GGTCCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009701.3 |
CDS | 1..1314 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178491.3 |
1 | ATGGATAACG AGGTTGAAAA AAATATTGAG ATCTGGAAGG TCAAGAAGTT GGTCCAATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |