Gene Symbol | MCM2 |
Entrez Gene ID | 852258 |
Full Name | MCM DNA helicase complex subunit MCM2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MCM2 cDNA ORF clone
Gene Symbol | MCM2 |
Entrez Gene ID | 852258 |
Full Name | MCM DNA helicase complex subunit MCM2 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001178263.1 | NP_009530.1 | MCM DNA helicase complex subunit MCM2 |
Pan troglodytes (chimpanzee) | MCM2 | XP_516724.2 |
MCM2 | XP_001099580.2 | |
Rattus norvegicus (Norway rat) | Mcm2 | NP_001101343.2 |
Xenopus tropicalis (tropical clawed frog) | mcm2 | NP_001006772.1 |
Canis lupus familiaris (dog) | MCM2 | XP_541736.3 |
Gallus gallus (chicken) | MCM2 | NP_001006139.1 |
Drosophila melanogaster (fruit fly) | Mcm2 | NP_477121.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004275 | XP_313198.5 |
Kluyveromyces lactis | KLLA0F12584g | XP_455649.1 |
Arabidopsis thaliana (thale cress) | MCM2 | NP_175112.2 |
Oryza sativa (rice) | Os11g0484300 | NP_001067910.1 |
Bos taurus (cattle) | MCM2 | XP_002707828.1 |
Mus musculus (house mouse) | Mcm2 | NP_032590.2 |
Caenorhabditis elegans (roundworm) | mcm-2 | NP_001022416.1 |
Saccharomyces cerevisiae (baker's yeast) | MCM2 | NP_009530.1 |
Eremothecium gossypii | AGOS_AFR178W | NP_985725.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_08122 | XP_003715082.1 |
Neurospora crassa | NCU04327 | XP_960973.1 |
Homo sapiens (human) | MCM2 | NP_004517.2 |
Danio rerio (zebrafish) | mcm2 | NP_775364.1 |
Schizosaccharomyces pombe (fission yeast) | mcm2 | NP_595477.1 |
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Complete DNA sequence of yeast chromosome II.
Feldmann H, Aigle M, Aljinovic G, Andr? B, Baclet MC, Barthe C, Baur A, B?cam AM, Biteau N, Boles E, Brandt T, Brendel M, Br?ckner M, Bussereau F, Christiansen C, Contreras R, Crouzet M, Cziepluch C, D?molis N, Delaveau T, Doignon F, Domdey H, D?sterhus S, Dubois E, Dujon B, El Bakkoury M, Entian KD, Feurmann M, Fiers W, Fobo GM, Fritz C, Gassenhuber H, Glandsdorff N, Goffeau A, Grivell LA, de Haan M, Hein C, Herbert CJ, Hollenberg CP, Holmstr?m K, Jacq C, Jacquet M, Jauniaux JC, Jonniaux JL, Kalles?e T, Kiesau P, Kirchrath L, K?tter P, Korol S, Liebl S, Logghe M, Lohan AJ, Louis EJ, Li ZY, Maat MJ, Mallet L, Mannhaupt G, Messenguy F, Miosga T, Molemans F, M?ller S, Nasr F, Obermaier B, Perea J, Pi?rard A, Piravandi E, Pohl FM, Pohl TM, Potier S, Proft M, Purnelle B, Ramezani Rad M, Rieger M, Rose M, Schaaff-Gerstenschl?ger I, Scherens B, Schwarzlose C, Skala J, Slonimski PP, Smits PH, Souciet JL, Steensma HY, Stucka R, Urrestarazu A, van der Aart QJ, van Dyck L, Vassarotti A, Vetter I, Vierendeels F, Vissers S, Wagner G, de Wergifosse P, Wolfe KH, Zagulski M, Zimmermann FK, Mewes HW, Kleine K
The EMBO journal13(24)5795-809(1994 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-alpha to Mcm2-7.
Title: An intact Mcm10 coiled-coil interaction surface is important for origin melting, helicase assembly and the recruitment of Pol-? to Mcm2-7.
Mcm10 directly binds the Minichromosome Maintenance Complex via Mcm2 and the Mcm6 C terminus.
Title: Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex.
Data show that Dbf4-dependent kinase (DDK)-phosphoryled MCM DNA helicase complex subunit MCM2 preferentially interacts with DNA replication initiation factor CDC45.
Title: Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase.
Mcm2-7 and specifically the ATPase site inactivated by mcm2DENQ are required at an intermediate step of the DNA replication checkpoint signal transduction cascade.
Title: Mcm2-7 Is an Active Player in the DNA Replication Checkpoint Signaling Cascade via Proposed Modulation of Its DNA Gate.
Mcm2-7 phosphorylation and firing factor recruitment promote complete and semi-conservative replication of the input plasmids.
Title: Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication.
The following MCM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MCM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01687 | |
Clone ID Related Accession (Same CDS sequence) | NM_001178263.1 | |
Accession Version | NM_001178263.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2607bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | MCM DNA helicase complex subunit MCM2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001134). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGATA ATAGAAGACG TAGACGTGAG GAAGATGATT CGGACTCAGA AAATGAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_009530.1 |
CDS | 1..2607 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001178263.1 |
1 | ATGTCTGATA ATAGAAGACG TAGACGTGAG GAAGATGATT CGGACTCAGA AAATGAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Life with 6000 genes. |
Complete DNA sequence of yeast chromosome II. |