HMO1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene
Clones
gRNAs

Summary

Gene Symbol	HMO1
Entrez Gene ID	851754
Full Name	Hmo1p
Synonyms	HSM2
Gene Type	protein-coding
Organism	Saccharomyces cerevisiae S288C

mRNA and Protein(s)

mRNA	Protein	Name
NM_001180481.1	NP_010459.1	Hmo1p

Pathways from BioSystems

Homologies

Saccharomyces cerevisiae (baker's yeast)	HMO1	NP_010459.1
Eremothecium gossypii	AGOS_AGL141W	NP_986526.1
Kluyveromyces lactis	KLLA0D18029g	XP_453858.1

Gene Ontology
Bibliography

Related articles in PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)

Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Persistent induction of DNA double-strand breaks or mTORC1 inhibition by rapamycin results in reduced levels of HMO1 mRNA, but only in the presence of Tor1p. This down-regulation is accompanied by eviction of Ifh1p and recruitment of Crf1p, followed by concerted dissociation of Hmo1p and Tor1p.
Title: DNA damage regulates direct association of TOR kinase with the RNA polymerase II-transcribed

Hmo1p functions to control DNA end resection, thereby preventing error-prone A-EJ repair and directing repairs towards classical NHEJ. The very low efficiency of DSB repair in kuDeltahmo1Delta cells further suggests that excessive DNA resection is inhibitory for A-EJ.
Title: Control of DNA end resection by yeast Hmo1p affects efficiency of DNA end-joining.

studied the genome-wide binding patterns of Nhp6, Hmo1 and the SWI/SNF complex, finding that most of gene promoters presenting high occupancy of this complex also display high enrichment of these HMG proteins.
Title: Role of Nhp6 and Hmo1 in SWI/SNF occupancy and nucleosome landscape at gene regulatory regions.

HMO1 appears to have evolved a unique linker histone-like function involving the ability to stabilize both conventional nucleosome arrays as well as DNA regions characterized by low nucleosome density or the presence of noncanonical nucleosomes.
Title: Yeast HMO1: Linker Histone Reinvented.

Saccharomyces cerevisiae HMGB protein HMO1 stabilizes chromatin as evidenced by faster chromatin remodeling in its absence.
Title: Yeast high mobility group protein HMO1 stabilizes chromatin and is evicted during repair of DNA double strand breaks.

The following HMO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HMO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OSi01257	NM_001180481.1 Latest version!	Saccharomyces cerevisiae S288C Hmo1p (HMO1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HMO1 ( NM_001180481.1 ) cDNA ORF clone, Saccharomyces cerevisiae S288C -> NP_010459.1 Saccharomyces cerevisiae S288C Hmo1p (HMO1), partial mRNA.

Price & Availability↑

CloneID	OSi01257
Clone ID Related Accession (Same CDS sequence)	NM_001180481.1
Accession Version	NM_001180481.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 741bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-31
Organism	Saccharomyces cerevisiae S288C
Product	Hmo1p
Comment	Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends.

ATGACTACAG ATCCTTCTGT CAAATTGAAG TCCGCCAAAG ACTCCCTCGT CTCCTCCCTC 
TTCGAGTTAT CAAAAGCTGC TAATCAGACA GCCTCCTCTA TTGTTGATTT CTACAATGCC 
ATCGGCGACG ATGAAGAAGA GAAGATAGAG GCTTTCACCA CTTTGACTGA GTCTTTGCAA 
ACATTGACTT CTGGTGTAAA CCACTTGCAC GGCATCAGCT CGGAGCTGGT TAACCCTATT 
GATGATGATA AAGATGCTAT TATCGCTGCT CCAGTCAAGG CTGTAAGAAG AAAGATCGAA 
CGTGATCCAA ATGCTCCAAA GAAGCCACTG ACTGTTTTCT TTGCTTACTC TGCGTACGTT 
CGTCAAGAAC TTCGTGAAGA CAGACAAAAG GCTGGCTTGC CACCTTTATC CTCAACTGAG 
ATTACTCAAG AAATCTCCAA GAAATGGAAG GAATTGAGTG ATAACGAAAA AGAAAAATGG 
AAGCAGGCTT ACAACGTCGA GTTGGAGAAT TACCAAAGAG AGAAATCCAA ATACTTAGAA 
GCAAAGAAAA ACGGTACCCT ACCACCAGCT TCCTTGGAAA ACGGTCCAAC TCATGCGCCG 
GTTCCAATTC CTTTCAGTTT ACAGCACGCC GCTGAACCTC CTGTGGAAAA GAGACCTCAC 
GATGATGATG GATCTTCGGA AAAGAAGAAG AAGAAGAAGA AGAAGGATAA GAAGAAGGAC 
AAATCCAACT CTTCTATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_010459.1
CDS	1..741
Translation	MTTDPSVKLKSAKDSLVSSLFELSKAANQTASSIVDFYNAIGDDEEEKIEAFTTLTESLQTLTSGVNHLHGISSELVNPIDDDKDAIIAAPVKAVRRKIERDPNAPKKPLTVFFAYSAYVRQELREDRQKAGLPPLSSTEITQEISKKWKELSDNEKEKWKQAYNVELENYQREKSKYLEAKKNGTLPPASLENGPTHAPVPIPFSLQHAAEPPVEKRPHDDDGSSEKKKKKKKKDKKKDKSNSSI

Target ORF information:

RefSeq Version	NM_001180481.1
Organism	Saccharomyces cerevisiae S288C
Definition	Saccharomyces cerevisiae S288C Hmo1p (HMO1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001180481.1

ORF Insert Sequence:

ATGACTACAG ATCCTTCTGT CAAATTGAAG TCCGCCAAAG ACTCCCTCGT CTCCTCCCTC 
TTCGAGTTAT CAAAAGCTGC TAATCAGACA GCCTCCTCTA TTGTTGATTT CTACAATGCC 
ATCGGCGACG ATGAAGAAGA GAAGATAGAG GCTTTCACCA CTTTGACTGA GTCTTTGCAA 
ACATTGACTT CTGGTGTAAA CCACTTGCAC GGCATCAGCT CGGAGCTGGT TAACCCTATT 
GATGATGATA AAGATGCTAT TATCGCTGCT CCAGTCAAGG CTGTAAGAAG AAAGATCGAA 
CGTGATCCAA ATGCTCCAAA GAAGCCACTG ACTGTTTTCT TTGCTTACTC TGCGTACGTT 
CGTCAAGAAC TTCGTGAAGA CAGACAAAAG GCTGGCTTGC CACCTTTATC CTCAACTGAG 
ATTACTCAAG AAATCTCCAA GAAATGGAAG GAATTGAGTG ATAACGAAAA AGAAAAATGG 
AAGCAGGCTT ACAACGTCGA GTTGGAGAAT TACCAAAGAG AGAAATCCAA ATACTTAGAA 
GCAAAGAAAA ACGGTACCCT ACCACCAGCT TCCTTGGAAA ACGGTCCAAC TCATGCGCCG 
GTTCCAATTC CTTTCAGTTT ACAGCACGCC GCTGAACCTC CTGTGGAAAA GAGACCTCAC 
GATGATGATG GATCTTCGGA AAAGAAGAAG AAGAAGAAGA AGAAGGATAA GAAGAAGGAC 
AAATCCAACT CTTCTATTTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Nature387(6632 Suppl)75-8(1997 May)
Jacq C,Alt-M?rbe J,Andre B,Arnold W,Bahr A,Ballesta JP,Bargues M,Baron L,Becker A,Biteau N,Bl?cker H,Blugeon C,Boskovic J,Brandt P,Br?ckner M,Buitrago MJ,Coster F,Delaveau T,del Rey F,Dujon B,Eide LG,Garcia-Cantalejo JM,Goffeau A,Gomez-Peris A,Zaccaria P

Life with 6000 genes.
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
Goffeau A,Barrell BG,Bussey H,Davis RW,Dujon B,Feldmann H,Galibert F,Hoheisel JD,Jacq C,Johnston M,Louis EJ,Mewes HW,Murakami Y,Philippsen P,Tettelin H,Oliver SG

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

HMO1 cDNA ORF clone, Saccharomyces cerevisiae S288C

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報