Gene Symbol | SUP35 |
Entrez Gene ID | 851752 |
Full Name | translation termination factor GTPase eRF3 |
Synonyms | GST1,PNM2,SAL3,SUF12,SUP2,SUP36 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » SUP35 cDNA ORF clone
Gene Symbol | SUP35 |
Entrez Gene ID | 851752 |
Full Name | translation termination factor GTPase eRF3 |
Synonyms | GST1,PNM2,SAL3,SUF12,SUP2,SUP36 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180479.3 | NP_010457.3 | translation termination factor GTPase eRF3 |
Pan troglodytes (chimpanzee) | GSPT1 | XP_001140542.3 |
Rattus norvegicus (Norway rat) | Gspt1 | NP_001003978.1 |
Gallus gallus (chicken) | GSPT1 | NP_001129149.1 |
Saccharomyces cerevisiae (baker's yeast) | SUP35 | NP_010457.3 |
Homo sapiens (human) | GSPT1 | NP_001123478.1 |
Danio rerio (zebrafish) | gspt1 | NP_001003992.1 |
Kluyveromyces lactis | KLLA0D17424g | XP_453831.1 |
Oryza sativa (rice) | Os04g0270100 | NP_001052341.1 |
LOC716860 | XP_001107851.2 | |
Bos taurus (cattle) | GSPT1 | NP_001091540.2 |
Mus musculus (house mouse) | Gspt1 | NP_001123480.1 |
Rattus norvegicus (Norway rat) | LOC100911685 | XP_006245802.1 |
Eremothecium gossypii | AGOS_AGL145W | NP_986522.2 |
Danio rerio (zebrafish) | gspt1l | NP_942101.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP009310 | XP_320105.3 |
Schizosaccharomyces pombe (fission yeast) | sup35 | NP_588225.1 |
Neurospora crassa | NCU04790 | XP_960416.1 |
Arabidopsis thaliana (thale cress) | AT1G18070 | NP_001185026.1 |
Canis lupus familiaris (dog) | GSPT1 | XP_005621589.1 |
Drosophila melanogaster (fruit fly) | Elf | NP_001260415.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00449 | XP_003718618.1 |
Xenopus tropicalis (tropical clawed frog) | gspt1 | NP_001015805.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
proteolytic cleavage of Sup35 suppresses spontaneous de novo generation of the [PSI(+)] prion.
Title: Proteolysis suppresses spontaneous prion generation in yeast.
curing by Hsp104 overexpression depends on both the trimming ability of the fungal Hsp104 homolog and the strength of the [PSI(+)] variant: the greater the trimming activity of the Hsp104 homolog and the weaker the variant, the greater the curing.
Title: Heat shock protein 104 (Hsp104)-mediated curing of [
Sup35 becomes oxidized and aggregates during oxidative stress conditions and plays a role in [PSI+] prion formation.
Title: Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [PSI+] prion formation.
results show that the presence of Rnq1p in the cell significantly decreases the loss of [PSI;(+)] prion, which is caused by a double mutation in SUP35 (Q61K, Q62K substitutions in the Sup35 protein).
Title: [Rnq1 protein protects [PSI^(+)] prion from effect of the PNM mutation].
we discovered a non-chromosomal factor, [NSI+], which possesses the main features of yeast prions, including cytoplasmic infectivity, reversible curability, dominance, and non-Mendelian inheritance in meiosis. This factor causes omnipotent suppression of nonsense mutations in strains of S. cerevisiae bearing a deleted or modified Sup35 N-terminal domain
Title: Interaction of Prions Causes Heritable Traits in Saccharomyces cerevisiae.
The following SUP35 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SUP35 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01255 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180479.3 | |
Accession Version | NM_001180479.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2058bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | translation termination factor GTPase eRF3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). On Jul 30, 2012 this sequence version replaced NM_001180479.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCGGATT CAAACCAAGG CAACAATCAG CAAAACTACC AGCAATACAG CCAGAACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010457.3 |
CDS | 1..2058 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180479.3 |
1 | ATGTCGGATT CAAACCAAGG CAACAATCAG CAAAACTACC AGCAATACAG CCAGAACGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |