Gene Symbol | MSH6 |
Entrez Gene ID | 851671 |
Full Name | mismatch repair ATPase MSH6 |
Synonyms | PMS3,PMS6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » MSH6 cDNA ORF clone
Gene Symbol | MSH6 |
Entrez Gene ID | 851671 |
Full Name | mismatch repair ATPase MSH6 |
Synonyms | PMS3,PMS6 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180405.3 | NP_010382.3 | mismatch repair ATPase MSH6 |
Danio rerio (zebrafish) | msh6 | NP_878280.1 |
Drosophila melanogaster (fruit fly) | Msh6 | NP_648755.1 |
Caenorhabditis elegans (roundworm) | msh-6 | NP_491163.1 |
Saccharomyces cerevisiae (baker's yeast) | MSH6 | NP_010382.3 |
Kluyveromyces lactis | KLLA0C17732g | XP_452992.1 |
Xenopus tropicalis (tropical clawed frog) | msh6 | XP_002935421.2 |
Pan troglodytes (chimpanzee) | MSH6 | XP_003309101.1 |
Mus musculus (house mouse) | Msh6 | NP_034960.1 |
Eremothecium gossypii | AGOS_AGR116W | NP_986782.2 |
Canis lupus familiaris (dog) | MSH6 | XP_531814.2 |
Gallus gallus (chicken) | MSH6 | XP_419359.3 |
Schizosaccharomyces pombe (fission yeast) | msh6 | NP_588344.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00704 | XP_003718302.1 |
Homo sapiens (human) | MSH6 | NP_000170.1 |
MSH6 | XP_001113749.1 | |
Bos taurus (cattle) | MSH6 | NP_001179666.1 |
Rattus norvegicus (Norway rat) | LOC100360342 | XP_006239796.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003190 | XP_312887.5 |
Neurospora crassa | NCU08135 | XP_959678.2 |
Arabidopsis thaliana (thale cress) | MSH6 | NP_192116.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Msh2-Msh6 slides without hopping and is largely blocked by protein roadblocks.
Title: Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions.
Msh2-Msh6 localizes PCNA to repair sites after mispair recognition.
Title: PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair.
analysis of the interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex
Title: Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex.
results suggest that MSH2-MSH6 binding to homoduplex regions of DNA recruits NHP6A, which then prevents further binding of MSH2-MSH6 to these sites unless a mismatch is present.
Title: Modulation of the DNA-binding activity of Saccharomyces cerevisiae MSH2-MSH6 complex by the high-mobility group protein NHP6A, in vitro.
Interactions between Msh2-Msh6 and DNA are dominated by lateral movement of the protein along the helical axis and have implications for how MutS family members travel along DNA at different stages of the mismatch repair reaction.
Title: Dynamic basis for one-dimensional DNA scanning by the mismatch repair complex Msh2-Msh6.
The following MSH6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSH6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi01185 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180405.3 | |
Accession Version | NM_001180405.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | mismatch repair ATPase MSH6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). On Jul 30, 2012 this sequence version replaced NM_001180405.2. ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGCCCCAG CTACCCCTAA AACTTCTAAG ACTGCACACT TCGAAAATGG CTCCACATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010382.3 |
CDS | 1..3729 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180405.3 |
1 | ATGGCCCCAG CTACCCCTAA AACTTCTAAG ACTGCACACT TCGAAAATGG CTCCACATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |