Gene Symbol | CDC48 |
Entrez Gene ID | 851431 |
Full Name | AAA family ATPase CDC48 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC48 cDNA ORF clone
Gene Symbol | CDC48 |
Entrez Gene ID | 851431 |
Full Name | AAA family ATPase CDC48 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180185.1 | NP_010157.1 | AAA family ATPase CDC48 |
Pan troglodytes (chimpanzee) | VCP | XP_003312111.1 |
Gallus gallus (chicken) | VCP | NP_001038129.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_05193 | XP_003712735.1 |
Canis lupus familiaris (dog) | VCP | XP_852626.1 |
Bos taurus (cattle) | VCP | NP_001029466.1 |
Mus musculus (house mouse) | Vcp | NP_033529.3 |
Drosophila melanogaster (fruit fly) | TER94 | NP_477369.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005630 | XP_315644.3 |
Saccharomyces cerevisiae (baker's yeast) | CDC48 | NP_010157.1 |
Schizosaccharomyces pombe (fission yeast) | cdc48 | NP_593287.2 |
Neurospora crassa | NCU00018 | XP_957005.2 |
Arabidopsis thaliana (thale cress) | AT3G53230 | NP_190891.1 |
Rattus norvegicus (Norway rat) | Vcp | NP_446316.1 |
Danio rerio (zebrafish) | vcp | NP_958889.1 |
Kluyveromyces lactis | KLLA0F05676g | XP_455337.1 |
Arabidopsis thaliana (thale cress) | AT5G03340 | NP_568114.1 |
Oryza sativa (rice) | Os03g0151800 | NP_001048987.1 |
Xenopus tropicalis (tropical clawed frog) | vcp | NP_001005677.1 |
Caenorhabditis elegans (roundworm) | cdc-48.1 | NP_496273.1 |
Caenorhabditis elegans (roundworm) | cdc-48.2 | NP_495705.1 |
Arabidopsis thaliana (thale cress) | CDC48 | NP_187595.1 |
Homo sapiens (human) | VCP | NP_009057.1 |
Eremothecium gossypii | AGOS_AFR158W | NP_985705.2 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Identify the Cdc48-Rad23/Dsk2 axis as a major route to the proteasome.
Title: In?Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome.
Study elucidated the mechanism of Cdc48 from S. cerevisiae with purified components that include Cdc48 itself, its UN cofactor, and model substrates bearing K48-linked polyubiquitin chains.
Title: Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex.
Multispanning endoplasmic reticulum membrane proteins, called ERAD-M substrates, are retrotranslocated to the cytosol as full-length intermediates during Endoplasmic Reticulum-associated Degradation, and this study investigated how they maintain substrate solubility. the Cdc48 complex is generally and critically needed for the solubility of retrotranslocated ERAD-M intermediates.
Title: A Cdc48 "Retrochaperone" Function Is Required for the Solubility of Retrotranslocated, Integral Membrane Endoplasmic Reticulum-associated Degradation (ERAD-M) Substrates.
Data show that Saccharomyces cerevisiae proteins Rqc1, Ltn1, and Cdc48 prevent the aggregation of aberrant proteins that can only appear after C-terminal alanine-threonine tail (CAT-tail) addition by Rqc2.
Title: Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits.
Upon DNA damage Wss1/Cdc48/Doa1 ternary complex is recruited to sumoylated targets and catalyzes SUMO chain extension through a newly recognized SUMO ligase activity.
Title: Wss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugates.
The following CDC48 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC48 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00981 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180185.1 | |
Accession Version | NM_001180185.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2508bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | AAA family ATPase CDC48 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGGGTGAAG AACATAAACC ACTTTTGGAC GCCTCGGGTG TCGACCCTCG TGAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010157.1 |
CDS | 1..2508 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180185.1 |
1 | ATGGGTGAAG AACATAAACC ACTTTTGGAC GCCTCGGGTG TCGACCCTCG TGAGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |