Gene Symbol | CDC53 |
Entrez Gene ID | 851424 |
Full Name | cullin CDC53 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
ORF » Species Summary » Saccharomyces cerevisiae S288C » CDC53 cDNA ORF clone
Gene Symbol | CDC53 |
Entrez Gene ID | 851424 |
Full Name | cullin CDC53 |
Gene Type | protein-coding |
Organism | Saccharomyces cerevisiae S288C |
mRNA | Protein | Name |
---|---|---|
NM_001180191.1 | NP_010150.1 | cullin CDC53 |
Saccharomyces cerevisiae (baker's yeast) | CDC53 | NP_010150.1 |
Eremothecium gossypii | AGOS_ADR106W | NP_984202.2 |
Kluyveromyces lactis | KLLA0F05467g | XP_455328.1 |
Oryza sativa (rice) | Os01g0369200 | NP_001043049.1 |
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
Jacq C, Alt-M?rbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Bl?cker H, Blugeon C, Boskovic J, Brandt P, Br?ckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P
Nature387(6632 Suppl)75-8(1997 May)
Life with 6000 genes.
Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG
Science (New York, N.Y.)274(5287)546, 563-7(1996 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This ubiquitylation and degradation pathway acts on Met30 that is dissociated from Skp1. Unexpectedly, this pathway required the cullin component Cdc53/Cul1 but was independent of the other central SCF component Skp1
Title: Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis.
A dual E3 mechanism for Rub1 ligation to Cdc53.
Title: A dual E3 mechanism for Rub1 ligation to Cdc53.
binding of substrate-specific adaptors triggers release of Cand1/Lag2, whereas subsequent neddylation of the cullin facilitates the removal and prevents re-association of Lag2/Cand1
Title: Cullin neddylation and substrate-adaptors counteract SCF inhibition by the CAND1-like protein Lag2 in Saccharomyces cerevisiae.
The binding site for Dcn1 on Cdc53 is located approximately 18 A from the site of neddylation.
Title: Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.
the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination
Title: Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.
The following CDC53 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC53 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OSi00974 | |
Clone ID Related Accession (Same CDS sequence) | NM_001180191.1 | |
Accession Version | NM_001180191.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2448bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-31 | |
Organism | Saccharomyces cerevisiae S288C | |
Product | cullin CDC53 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by SGD. This record is derived from an annotated genomic sequence (NC_001136). ##Genome-Annotation-Data-START## Annotation Provider :: SGD Annotation Status :: Full Annotation Annotation Version :: R64-2-1 URL :: http://www.yeastgenome.org/ ##Genome-Annotation-Data-END## COMPLETENESS: incomplete on both ends. |
1 | ATGTCTGAGA CTCTGCCTAG ATCTGATGAT TTAGAGGCCA CTTGGAACTT TATAGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_010150.1 |
CDS | 1..2448 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001180191.1 |
1 | ATGTCTGAGA CTCTGCCTAG ATCTGATGAT TTAGAGGCCA CTTGGAACTT TATAGAGCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. |
Life with 6000 genes. |